Mark A. Borden

Research Interests

Colloid science, ultrasound, theranostics, oxygen delivery

My research group investigates the science and engineering of microbubbles, nanodrops and other colloidal suspensions for use in biomedical imaging and therapy. Current applications include ultrasound molecular imaging, ultrasound image-guided drug delivery and oxygen delivery. We also focus on molecular-level details of interfacial transport phenomena related to our engineered colloids. 

Societal Impact

Borden's laboratory develops medical technology to aid in the diagnosis and treatment of diseases, such as acute respiratory distress syndrome (ARDS), heart disease and cancer. We have spun out two companies (Respirogen Inc. and Advanced Microbubbles LLC) to commercialize this technology and translate it to hospitals and clinics.

Select Publications

• G Shakya, SE Hoff, S Wang, H Heinz, X Ding, MA Borden. Vaporizable endoskeletal droplets via tunable interfacial melting transitions. Science Advances 6 (14), eaaz7188 (2020).
• JS Lum, V Daeichin, DF Kienle, DK Schwartz, TW Murray, MA Borden. Changes in microbubble dynamics upon adhesion to a solid surface. Applied Physics Letters 116 (12), 123703 (2020).
• Borden, M. A. Intermolecular Forces Model for Lipid Microbubble Shells. Langmuir 35, 10042–10051 (2019).

Select Awards