Published: Oct. 7, 2013
Nanoly CEO Balaji Sridhar (third from left) and other members of the Nanoly Bioscience team.

Nanoly Bioscience and the University of Colorado recently entered into an option agreement that will enable the startup company to develop a technique developed in the labs of ChBE Distinguished Professor Kristi Anseth for protecting vaccines during delivery to rural and less-developed areas of the world. 

The most needed vaccines in developing countries are for measles, tetanus, polio, pertussis and diphtheria, all of which -- like most vaccines -- must be kept at between 35-45 degrees Fahrenheit (2-8 degrees Centigrade) during transportation, delivery and storage. Outside of this range, vaccines begin to degrade and become ineffective. Maintaining this “cold chain” during transportation and delivery is challenging even in developed areas, and storing vaccines at appropriate temperatures is a serious problem in remote areas where electricity is absent or unreliable.

A research team led by Anseth developed a unique material that is being adapted to solve the problem, which is estimated by the World Health Organization to cause more than a quarter of the total wastage of liquid vaccines worldwide. Anseth’s group created a unique “nano-polymer” material that can be customized and blended with any vaccine to protect against thermal damage during transportation, ultimately improving vaccine availability in remote locations.

“We’re thrilled to be adapting CU technology and working toward a solution for such an important problem,” said Balaji Sridhar, a member of Anseth’s lab who co-founded Nanoly in 2012 along with Anseth lab colleague Mark Tibbitt and co-founders from several other institutions. In 2013, the company placed second in the CU Denver business plan competition.  Nanoly Bioscience also won the Duke University Startup Challenge in 2012.

“We are excited that Nanoly has optioned Dr. Anseth’s polymer technology,” said MaryBeth Vellequette of the University of Colorado Technology Transfer Office, who is the director of technology transfer for CU-Boulder. “Nanoly has a very dynamic team that is passionate about developing this technology and we are eager to continue working with them as this venture grows.”

About Nanoly Bioscience
Nanoly Bioscience is a new startup company developing a polymer based stabilization technique for temperature sensitive biologics and therapeutics. The intention is to eliminate the need for refrigeration during transportation and extend availability of the vaccine or therapeutic. www.nanoly.info.

About CU's Technology Transfer Office
The CU Technology Transfer Office pursues, protects, packages and licenses to business the intellectual property generated from research at CU. The office provides assistance to faculty, staff and students, as well as to businesses looking to license or invest in CU technology. For more information about technology transfer at CU visit http://www.cu.edu/techtransfer.  

[pictured at top: Nanoly CEO Balaji Sridhar (third from left) and other members of the Nanoly team]