Integrative Physiology of Aging Laboratory
Phone: 303-735-6410
Fax: 303-735-4799

Online Screening Form

If you are interested in participating in a study, please contact a researcher at 303-735-6410 or ipalab@colorado.edu. In addition, you can fill out our online screening form, which consists of questions that help us determine whether or not you qualify for a study. Each study is different and has different requirements for qualification. The research projects listed on this page are in various phases of recruitment. While projects may be ending recruitment, others may be just getting started, so if you are interested in research but don't qualify for a study at this time, please keep checking back.

COVID-19

We are taking measures to ensure subject and staff safety, including: social distancing when possible, requiring masks to be worn while in our facility, thoroughly sanitizing equipment the subject and staff come in contact with, requiring subjects and staff to answer a COVID-19 screening tool before coming in to the lab, and minimizing the number of staff each subject comes in contact with. Each staff member undergoes campus-required COVID-19 monitoring on a weekly basis. Please contact us if you have further questions about our measures to ensure your safety.

Research Initiatives

Ideal volunteers for the following research initiatives, with the exception of the beetroot juice and heat therapy studies, are healthy adults who are free of cardiovascular disease and other chronic health problems. Most medications are okay for the studies.

  • Beetroot juice supplementation in individuals with CKD/kidney dysfunction. This study will determine the effectiveness of beetroot juice for improving body functions, including blood vessel, physical, and brain function in adults (ages 30-80) with Chronic Kidney Disease/kidney dysfunction. It involves daily consumption of approximately 1/3rd cup of nitrate-rich (treatment) beetroot juice or nitrate-depleted (control) beetroot juice for three months with vascular measures before, during, and after the intervention. If you are interested in seeing if you might qualify to participate, please call 303-735-6410 or email beetrootstudy@colorado.edu.
  • The role of cellular senescence in cardiovascular aging. Seeking adults ages 18 to 79 to participate in a clinical study to learn how aging and exercise affects the function of your blood vessels. Participants will receive blood cholesterol and blood sugar measures, body fat measurements, blood pressure screening, as well as a physical exam and stress test to check heart health. Compensation for your time and participation is available, if you qualify. For more information, please e-mail ipalab@colorado.edu, or call (303) 735-6410.
  • Passive heat therapy for lowering systolic blood pressure and improving vascular function in mid-life and older adults. We are looking for women and men, ages 50+, who are willing to participate in water immersion sessions ~3 times per week for 12 weeks. Benefits for volunteers include: cardiovascular health assessment, exercise stress test, body composition, and blood chemistries. For more information, please e-mail cvstudy.cuboulder@gmail.com, or call (303) 735-4936.
  • Nicotinamide riboside supplementation in individuals with above average systolic blood pressure. The purpose of this study is to look at the effects of nicotinamide riboside (NR) on body functions in adults 50 years or older with above-normal blood pressure. This study involves NR supplementation twice daily for 3 months. Participants will be tested for blood pressure, a complete blood panel, cardiovascular health, and cognitive function before and after the 3-month supplementation period. If you are interested in participating in this study, please call 303-492-2485 or email nrstudy@colorado.edu.
  • Seals Study IMST male participant 300pxInspiratory muscle strength training in individuals with above average systolic blood pressure. This study examines the effects of inspiratory muscle strength training (IMST) on body functions in adults 50 years or older with above-normal blood pressure. Subjects will perform a breathing exercise for 5 minutes per day, 6 days per week for 3 months, or subjects will perform 25 minutes of brisk walking per day, 6 days per week for 3 months. Participants will be tested for blood pressure, a complete blood panel, cardiovascular health, vascular function and cognitive function before and after the 3-month intervention period. If you are interested in participating in this study, please call 303-492-2485 or email imststudy@colorado.edu.
  • Mitochondria-targeted antioxidant supplementation for older adults. The purpose of this study is to study the effects of mitoquinol (MitoQ), an antioxidant that is attracted to the mitochondria of cells, on cardiovascular and brain function in adults 60 years or older. It involves consuming a MitoQ or placebo pill once a day for three months. Participants will be tested for blood pressure, a complete blood panel, cardiovascular health, vascular function and cognitive function before and after the 3-month intervention period. If you are interested in participating in this study, please call 303-735-6410 or email mitoqstudy@colorado.edu.

Qualified participants receive:

  • Free medical screening and diagnostic testing (bone scans, exercise stress tests, ultrasound, blood tests) completed by professional medical personnel.
  • Financial compensation for your participation.

Helpful and/or important information about our research:

  • All studies have passed rigorous examination by the University Ethical Research Review Board and are supported by the National Institutes of Health.
  • Studies take place at the Ramaley Biology building, located near the campus recreation center on the CU Boulder main campus.
  • In general, visits take place in the morning, beginning between 7:00 am and 11:00 am Monday through Friday.