subject being tested with a respirometer

3100 Marine Street, Room A53
Administrative Research Center, 554 UCB
Boulder, CO 80309-0554
Lab Phone: 303-735-0358
Fax: 303-735-4125

Research Interests

  • The focus of the Applied Exercise Science Laboratory (AESL) is to examine
    changes associated with long- and short-term physical activity and to determine
    the role of these changes in improving health and athletic performance.


  • Director: William C. Byrnes, Ph.D.
  • Doctoral Students: Eric Homestead, James Peterman, Jesse Goodrich.
  • Masters Students: Alex Cross, Sewan Kim.
  • BA/MS Students: Kalee Morris.
  • Undergraduate Students: Lauren Davis, Nicholas Milburn, Jenna Turner, Nancy Best, Mackenzie Whitcomb, Uma Hatangadi.
  • Collaborators: Rodger Kram, Ph.D., Locomotion Laboratory, University of Colorado Boulder; David Allen, Ph.D., Department of Psychology and Neuroscience, University of Colorado Boulder; Edward Melanson, Ph.D., Division of Endocrinology, Metabolism, and Diabetes, University of Colorado - School of Medicine; Randall Wilber, Ph.D., Performance Services, United States Olympic Committee; Walter Schmidt, Ph.D. and Nadine Wachsmth, Ph.D., Department of Sports Medicine, University of Bayreuth, Germany; Kenneth P. Wright Jr., Ph.D., Sleep and Chronobiology Laboratory, University of Colorado at Boulder.

Measuring the energetics of load-carrying in Nepal

Measuring the energetics of load-carrying in Nepal

Current Research Projects

  • To investigate how interventions that promote physical activity and limit sedentary sitting impact cardiometabolic risk factors.
  • To examine the factors that influence the energetics of exercise.
  • To investigate hemoglobin mass adaptations to short-term environmental perturbations.
  • To investigate the role of connective tissue in exercise-induced muscle damage and repair in humans.
  • To examine interactions between hemoglobin mass, arterial oxygen saturation, and maximal oxygen uptake.
  • To investigate the role of airflow resistance on physiological responses during exercise.

Recent Publications

  • Kane LA, Ryan BJ, Schmidt WF, Byrnes WC. Acute, low-dose CO inhalation does not alter energy expenditure during submaximal exercise. International Journal of Sports Medicine 37.01: 19-24, 2016.
  • Peterman JE, Lim AC, Ignatz RI, Edwards AG, Byrnes WC. Field-Measured Drag Area is a Key Correlate of Level Cycling Time Trial Performance. PeerJ 3: e1144, 2015.
  • Peterman JE, Morris KL, Kram R, Byrnes WC. Pedelecs as a Physically Active Transportation Mode. European Journal of Applied Physiology 116: 1565-73, 2016.
  • Peterman JE, Wright Jr. KP, Melanson EL, Kram R, Byrnes WC. Motor-driven (passive) cycling: a potential physical inactivity countermeasure? Medicine and Science in Sports and Exercise 48: 1821-1828, 2016.
  • Ryan BJ, Goodrich JG, Schmidt W, Kane LA, Byrnes WC. Ten Days of Intermittent, Low-dose Carbon Monoxide Inhalation does not significantly alter Hemoglobin Mass, Aerobic Performance Predictors, or Peak-power Exercise Tolerance. International Journal of Sports Medicine 2016. DOI 10.1055/s-0042-108197.
  • Ryan BJ, Wachsmuth NB, Schmidt WF, Byrnes WC, Julian CG, Lovering AT, Subudhi AW, Roach RC. AltitudeOmics: rapid hemoglobin mass alterations with early acclimatization to and de-acclimatization from 5260 m in healthy humans. PLoS ONE 9: e108788, 2014.
  • Welsh MC, Allen DL, Batliner ME, Byrnes WC. Revisiting the Force-Joint Angle Relationship After Eccentric Exercise. The Journal of Strength & Conditioning Research 29.12: 3284-3291, 2015.
  • Welsh MC, Allen DL, Byrnes WC. Plasma matrix metalloproteinase-9 response to downhill running in humans. International journal of sports medicine 35: 363-370, 2014.