High-Throughput Screening Core Facility
Information about the High-Throughput Screening Core Facility
Contact: Wei Wang
Website: http://www.colorado.edu/lab/hts/instruments
Instruments
The Biomek® FXP Laboratory Automation Workstation puts every aspect of liquid handling – including pipetting, dilution, dispensing and integration – into a single, automated system that is as powerful and flexible as it is efficient and economical.
The Thermo Scientific ArrayScan VTI HCS Reader is a modular, flexible imaging platform, designed for high-capacity, automated, quantitative cellular and sub-cellular analysis in fixed and live cell formats.From investigative cell biology to high throughput high content screening, the ArrayScan VTI HCS Reader has a proven track record with over 450 peer-reviewed publications in research areas as diverse as understanding childhood liver disease, through to the search for cures for spinal injury to understanding drug failures due to toxicity.
The CyBi®-Well pipettor can be configured with for 96 or 384 channels and has a volume range of 200 nL to 250 µL. In only 20 seconds, it pipettes and transports a 384-well microplate; in 30 seconds and·in just four steps, it process 1536-well microplates. Procedures can be quickly and easily programmed with the CyBio® Composer software.
EnVision® reads all non-isotopic detection technologies, including fluorescence intensity, fluorescence polarization, time-resolved fluorescence (TRF), luminescence and absorbance, in all major applications. It features label-specific optical mirror modules, high-energy flash lamps and high-speed detectors. The plate conveyor and stackers have been optimized to achieve maximum possible speed, with parallel functionality as well as fast physical movements. The EnVision® instruments are easily integrated into robotic systems and are designed to provide the greatest configuration flexibility including accepting microplates from 1 to 3456 wells.