Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

Please see the full solicitation for complete information about the funding opportunity. Below is a summary assembled by the Research & Innovation Office (RIO).

Program Summary

The objective of the Program is to make available to institutions high-priced research instruments that can only be justified on a shared-use basis and that are needed for NIH-supported projects in basic, translational or clinical biomedical and bio-behavioral research. The SIG Program provides funds to purchase or upgrade a single item of expensive, state-of-the-art, specialized, commercially available instrument or an integrated instrumentation system. An integrated instrumentation system is one in which the components, when used in conjunction with one another, perform a function that no single component can provide. The components must be dedicated to the system and not used independently.

Types of supported instruments include, but are not limited to: X-ray diffractometers, mass spectrometers, nuclear magnetic resonance (NMR) spectrometers, DNA and protein sequencers, biosensors, electron and light microscopes, cell sorters, and biomedical imagers. Applications for standalone computer systems (supercomputers, computer clusters and data storage systems) will only be considered if the system is solely dedicated to biomedical research.

The SIG Program will not support requests for:

  • An instrument with a base cost of less than $50,000;
  • Multiple instruments bundled together;
  • Purely instructional equipment;
  • Instruments used for clinical (billable) care;
  • Institutional administrative management systems, clinical management systems;
  • Software, unless it is integrated in the operation of the instrument and/or necessary for generation of high-quality output experimental data from the instrument;
  • Stand-alone workstations for data processing, software licenses, and duplicate software items;
  • General purpose equipment (such as standard machine shop equipment), instruments to furnish a research facility (such as autoclaves, hoods, equipment to upgrade animal facilities), equipment for routine sustaining infrastructure (such as standard computer networks or data storage systems);
  • Disposable devices, office furniture, and supplies;
  • Alteration or renovation of space to house the instruments.

Deadlines

CU Internal Deadline: 11:59pm MST April 1, 2020

Sponsor Application Deadline: 5:00pm MST June 1, 2020

Internal Application Requirements (all in PDF format)

  • Project Summary (3 pages maximum): Please include the following: relevance to public health, description of requested instrument, justification of need, technical expertise of individuals who will set up and run the instrument, research projects that will be benefitted by the instrument, organizational/management plan, and financial plan for long-term operation and maintenance of the instrument.
  • PI Curriculum Vitae / Biosketch
  • Budget Overview (1 page maximum): A basic budget outlining project costs is sufficient; detailed OCG budgets are not required.

To access the online application, visit: https://cuboulderovcr.secure-platform.com/a/solicitations/6476/home

Eligibility

Three Major Users who have substantial need for the instrument must be identified. Each of these Major Users must be a PD/PI on a distinct active NIH research award (i.e., a grant or a cooperative agreement) in an area of basic, translational, or clinical research. The requirement is one award per investigator, with more awards per investigator allowed. An award given to multi-PDs/PIs is counted only once towards the fulfillment of this requirement. NIH training or fellowship grants (i.e., T and F mechanisms), other non-research and SBIR/STTR grants, Other Transaction (OT) awards, and contracts cannot be counted towards the fulfillment of this requirement. Once the eligibility requirement of three Major Users with distinct NIH-funded research projects has been met, additional users with active research awards from NIH or other sources may be added as Major or Minor Users. Investigators with funding from sources such as other Federal agencies (e.g., NSF, DoE, DoD), private foundations, or academic institutions, can be added as Major Users, provided they are engaged in basic, translational or clinical research and can demonstrate a substantial need for the instrument. Major Users can be researchers from the same department or from several departments, divisions or schools at the applicant institution, or from nearby or regional institutions. In certain circumstances, as technology dictates, Major Users may come from distant institutions, but they must demonstrate the need for the instruments and describe plans for regular access to the instrument.

Limited Submission Guidelines

Applicant organizations may submit more than one application, provided that each application is scientifically distinct.

Award Information

Award Amount: Minimum award is $50,000 of direct costs. Maximum award is $600,000 of direct costs.

Award Duration: One year only

Number of Awards: 75

Review Criteria

Please consider NIH’s specific review criteria as the proposal is developed. The internal review committee will use these criteria as a guide when evaluating internal proposals.