NIH Collaborative Program Grant for Multidisciplinary Teams (RM1) (Clinical Trial Not Allowed)

Please see the full solicitation for complete information about the funding opportunity. Below is a summary assembled by the Research & Innovation Office (RIO).

Program Summary

This funding opportunity announcement (FOA) is designed to support highly integrated research teams of three to six PD/PIs to address ambitious and challenging research questions that are important for the mission of NIGMS and are beyond the scope of one or two investigators. Collaborative program teams are expected to accomplish goals that require considerable synergy and managed team interactions. Project goals should not be achievable with a collection of individual efforts or projects. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields.

Applications that are mainly focused on the creation, expansion, and/or maintenance of community resources, creation of new technologies or infrastructure development are not appropriate for this FOA.


CU Internal Deadline: 11:59pm MT February 20, 2020

Sponsor Letter of Intent Deadline: 5:00pm MT April 25, 2020

Sponsor Application Deadline: 5:00pm MT May 25, 2020

Internal Application Requirements (all in PDF format)

  • Research Program (2 pages maximum): Proposed research should be presented as an integrated scientific program with a single set of specific aims organized to address the overall objectives rather than individual PD/PI contributions. The applicant should fully describe the biomedical problem being addressed, its significance within the relevant scientific field(s) and how successful accomplishment of the goals would provide substantial scientific advances.
  • Team Management Plan (1 page maximum): Overall team management plan that addresses how the entire group will function to accomplish program objectives and vision (e.g., the appropriate organizational structure and team composition; shared leadership, contributions and distributed responsibility for decision making, resource allocation, plans for professional development, conflict resolution).
  • Budget Overview (1 page maximum): A basic budget outlining project costs is sufficient; detailed OCG budgets are not required.

To access the online application, visit:


The application is required to be submitted as a multiple PD/PI application, with a minimum of 3 and a maximum of 6 PD/PIs.

PD/PIs who have an active NIGMS R35 award can participate as PD/PIs as part of the 51% effort on their current R35 award but may not receive additional funds from this award. Applicants with substantial unrestricted research support may receive funding from this award as their one NIGMS grant award, or may participate in an unfunded advisory or consulting role without loss of their ability to receive one funded NIGMS grant, consistent with NIGMS policies.

Limited Submission Guidelines

Only one application per institution per review cycle is allowed.

Award Information and Duration

Award Amount: While applications may request research program budgets of up to $1.5 million direct costs per year, it is anticipated than most awards will be between $700,000 - $900,000 direct costs. The requested budget should be consistent with the number of PDs/PIs and the complexity and needs of the proposed programs. In addition to the research program budget, an additional $250,000 direct costs per year may be requested for exploratory pilot studies for ESIs.

Number of Awards: NIGMS anticipates supporting no more than 4-6 awards.

Award Term: Up to 5 years

Review Criteria

Please consider NIH’s specific review criteria as the proposal is developed. The internal review committee will use these criteria as a guide when evaluating internal proposals.