Arpeggio Biosciences Inc.
Engineering medicine based not on a single target, but on the biological network as a whole. Visit the Arpeggio Website
The University of Colorado Connection

Arpeggio Biosciences is a Boulder-based biotechnology company developing a high-throughput transcriptomics platform to map how chemical compounds influence gene expression across entire biological networks. Founded in 2017 by Joey Azofeifa (CU Boulder BioFrontiers Institute) and Robin Dowell (CU Boulder BioFrontiers Institute and Molecular, Cellular & Developmental Biology), the company originated from research conducted at CU's BioFrontiers Institute. Arpeggio's platform combines nascent RNA sequencing with machine learning to profile the immediate effects of drugs on gene expression, enabling the discovery of novel therapeutic targets for diseases such as cancer, chronic kidney disease and neurodegeneration. The company has raised over $20 million in funding, including a $17 million Series A round in 2022 led by Builders VC.
Funding Status and Investment Opportunities
- Industry Applications: Biotech, Therapeutics
- Funding Stage: Series B Round
- Contact for Investment Inquiries: Joey Azofeifa , Joey@arpeggiobio.com
In the News
- Six CU Boulder startups selected to present at the Rocky Mountain Life Science Investor Conference (2024)
- Arpeggio Biosciences raises $17M in Series A funding led by Builders VC (2022)
- CU spinout Arpeggio Bio gives startup advice in Y Combinator blog post (2021)
- BioFrontiers Institute and IQ Biology alum, Joey Azofeifa (Arpeggio Bio), Raises $3.2 Million in Seed Funding and is Named to the 2020 Forbes 30 Under 30 List in Healthcare (2020)
- CU Boulder startup Arpeggio Bio raises $3.2 Million in seed funding and CEO named to 2020 Forbes 30 Under 30 List in Healthcare (2020)
- CU Boulder brings together top spinoffs from Colorado research institutions for Destination Startup (2019)
- Boulder’s bioscience industry growing to critical mass (2018)
- Bioscience start-up sheds light on ‘dark DNA’ (2018)
Venture Partners Programs
Technology Development Funding

U.S. National Science Foundation (NSF)
This page was last updated on May 9, 2025. Please email vpnews@colorado.edu for corrections or updates
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