Faculty

The Arnoult lab focuses on genome stability, DNA repair and telomere biology.

My group does deep proteomic studies on blood from people with Down syndrome in order to discover what signaling protein alterations are responsible for the many phenotypes as well as their high level of variability.

Currently serving as Vice Chancellor for Diversity, Equity and Community Engagement.

My research leverages stem cells and induced cell fate change to study early development with a focus on epigenetics and post-transcriptional regulation.

My research is on chromosome ends (telomeres) and their replication by telomerase.

My research aims to better understand the mechanisms that ensure the fidelity of neuronal receptor function and thus axon guidance.

The Chuong lab is interested in the evolution of gene regulation in adaptation and disease.

Research in the Copley lab centers on the molecular evolution of catalysts and metabolic pathways.

My lab studies how pathogenic bacteria evade and manipulate the mammalian immune system. We also study the related science of identifying and developing new antibacterials.

My work explores the interplay between genes and environment, with special emphasis on the importance of social relationships in modulating mood and behavior.

My primary interest is in understanding transcriptional regulation: how does it work, evolve, and respond to perturbations?

The Garcea laboratory studies the structure and assembly of small DNA viruses, with emphasis on polyoma and papillomaviruses.

The Gold Lab today focuses on the utilization of biological and information technology to improve healthcare.

Han lab has engaged dynamic research programs addressing important biological problems related to human diseases, primarily using C. elegans and mouse genetics.

My main research interests are functional and structural analyses by 3-D cryo-electron microscopy of cytoskeletal assemblies and large macromolecular structures as well as cellular organelles.

My laboratory studies the functions of neurotrophic factors in development and their relevance to neurodegenerative disease using a blend of transgenic mouse technology and anatomical, cell biological, and molecular techniques.

The Junge lab integrates molecular and protein-biochemical methods, cell biology, -omics, mouse genetics, and histological analysis to understand the signaling pathways that mediate neuro-vascular interactions. These efforts help us to understand how normal biology is altered in disease, in particular retinal vascular diseases.

My research focuses on the molecular mechanisms underlying mesoderm formation, and neural crest induction, and tissue and organ patterning. I also study how to design, assess, and effectively teach students to understand, appreciate, and make use of molecular biology.

Dr. Knight's research has focused on developing concept assessments for student learning in biology, studying the impact of in-class work on student learning, and developing and measuring the impact of curricular changes and teacher training on both students and faculty.

Research in the Kralj lab focuses on creating new tools to study functions of molecules, cells, and organisms.

Dr. Krauter's research focuses primarily on understanding the relationship between the human microbial composition and human development and disease.

We conduct research on cardiac and skeletal muscle with emphasis on genetic diseases involving them.

I developed and maintain a suite of programs for analysis and visualization of electron microscopy tomograms.

The Niswander lab investigates mouse models of embryonic development to provide insights into fundamental developmental processes, major human birth defects and potential clinical therapies.

My research investigates the molecular mechanisms of membrane trafficking from endosomes to lysosomes, which have a major role in protein degradation.

Dr. Old is interested in the signaling networks that regulate cell growth and communication in multicellular organisms, and how defects in these networks drive cancer and neurodevelopmental disorders.

Our research group is investigating the mechanisms that regulate skeletal muscle regeneration, focusing on skeletal muscle stem cells.

Professor Orth studies cancer therapies at the molecular and cellular level.

Dr. Park's laboratory studies the biogenesis of a molecular machine known as the proteasome, a major protease in eukaryotes.

The Perkins group focuses on developing precision single-molecule techniques and applying them to answer a variety of biological questions.

The Sawyer lab studies viral immunity, viral evolution, and the transmission of viruses from animals to man.

The overarching goal of my group is to uncover the regulatory principles of vesicle-mediated cargo transport.

Dr. Singh's laboratory studies post-transcriptional gene regulation.

Our research is focused on molecular and supramolecular structures that facilitate communication between neurons at the chemical synapse and how such structures are perturbed in neurological disease.

Our goal is to understand how cells, tissues and organisms survive exposure to high energy radiation such as X-rays.

At present, we are investigating why these mitochondria normally remain hypo-polarized and what effects this may have on certain elements of the oolemma found to be essential for sperm docking and penetration.

Our lab is studying how proteins generate the shape of the endoplasmic reticulum.

I am interested in studying the genetic and epigenetic regulation of mammalian epidermal development as well as skin cancer.

Dr. Xue's research interests lie in studying the mechanisms of programmed cell death (or apoptosis), phospholipid asymmetry in biological membranes, mitochondrial inheritance, and radiation-induced bystander effects, as well as various human diseases associated with abnormalities in these fundamental biological processes.

We are interested in the elucidation of gene expression regulatory networks controlled by transcription factors and miRNAs among others in mammalian skin development, stem cells and cancer.