Jeff Lessem portrait
Research Associate
Institute for Behavioral Genetics
Jeff.Lessem@Colorado.edu
303-492-2843

Institute for Behavioral Genetics
University of Colorado Boulder
447 UCB
Boulder, CO 80309-0447

Research Interests:
Research into the methodology for detecting quantitative trait loci; particularly in relation to substance abuse disorders and conduct disorders.

Publications

Genetic and environmental influences on executive functions and intelligence in middle childhood

CU Boulder Authors: Lessem, Jeffrey; Friedman, Naomi P; Hewitt, John K
All Authors: Freis SM; Morrison CL; Lessem JM; Hewitt JK; Friedman NP
Published in: Developmental Science
Publication Date: 2022-01-01
Type: Journal Article

Screen time and early adolescent mental health, academic, and social outcomes in 9-and 10-year old children: Utilizing the Adolescent Brain Cognitive Development (SM) (ABCD) Study

CU Boulder Authors: Hewitt, John K; Lessem, Jeffrey
All Authors: Paulich KN; Ross JM; Lessem JM; Hewitt JK
Published in: PLoS One
Publication Date: 2021-09-08
Type: Journal Article

Genetic correlations between executive functions and intelligence in the adolescent brain cognitive development (ABCD) study

CU Boulder Authors: Friedman, Naomi P; Hewitt, John K; Lessem, Jeffrey
All Authors: Freis SM; Morrison CL; Lessem JM; Hewitt JK; Friedman NP
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2020-06-26
Type: Conference Proceeding

Do modifiable risk factors moderate the effect of APOE on cognitive decline?

CU Boulder Authors: Lessem, Jeffrey; Keller, Matthew C
All Authors: Ellingson JM; Border RC; Lessem JM; Llewellyn DJ; Kuzma E; Keller MC
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2020-06-26
Type: Conference Proceeding

Exploring ABCD phenotypes for future behavioral genetic analysis: screen time is associated with mental health, academic outcomes, and peer relationships

CU Boulder Authors: Lessem, Jeffrey; Hewitt, John K
All Authors: Paulich KN; Ross JM; Lessem JM; Hewitt JK
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2020-06-26
Type: Conference Proceeding

Investigating the causal effect of cannabis use on cognitive function with a quasi-experimental co-twin design

CU Boulder Authors: Hewitt, John K; Lessem, Jeffrey; Friedman, Naomi P; Rhee, Soo H
All Authors: Ross JM; Ellingson JM; Rhee SH; Hewitt JK; Corley RP; Lessem JM; Friedman NP
Published in: Drug and Alcohol Dependence
Publication Date: 2020-01-01
Type: Journal Article

The role of genetic and environmental influences on the association between childhood ADHD symptoms and BMI

CU Boulder Authors: Lessem, Jeffrey
All Authors: Do EK; Haberstick BC; Williams RB; Lessem JM; Smolen A; Siegler IC; Fuemmeler BF
Published in: International Journal of Obesity
Publication Date: 2019-01-01
Type: Journal Article

Heritability of screen time in the ABCD study

CU Boulder Authors: Lessem, Jeffrey
All Authors: Lessem J
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2018-06-20
Type: Conference Proceeding

Simple Sequence Repeats in the National Longitudinal Study of Adolescent Health: An Ethnically Diverse Resource for Genetic Analysis of Health and Behavior

CU Boulder Authors: Lessem, Jeffrey; Hewitt, Christina; Hewitt, John K
All Authors: Haberstick BC; Smolen A; Stetler GL; Tabor JW; Roy T; Casey HR; Pardo A; Roy F; Ryals LA; Hewitt C
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2014-09-01
Type: Journal Article

Marijuana use and impaired cognitive ability

CU Boulder Authors: Lessem, Jeffrey; Friedman, Naomi P; Stallings, Michael C
All Authors: Friedman N; Rhee S; Corley R; Lessem J; Stallings M; Young S; Wadsworth S; Hewitt J
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2014-06-18
Type: Conference Proceeding

Prevalence and correlates of alcohol and cannabis use disorders in the United States: Results from the national longitudinal study of adolescent health

CU Boulder Authors: Hewitt, John K; Lessem, Jeffrey
All Authors: Haberstick BC; Young SE; Zeiger JS; Lessem JM; Hewitt JK; Hopfer CJ
Published in: Drug and Alcohol Dependence
Publication Date: 2014-03-01
Type: Journal Article

MAOA Genotype, Childhood Maltreatment, and Their Interaction in the Etiology of Adult Antisocial Behaviors

CU Boulder Authors: Boardman, Jason D; Lessem, Jeffrey; Hewitt, John K
All Authors:
Haberstick BC; Lessem JM; Hewitt JK; Smolen A; Hopfer CJ; Halpern CT; Killeya-Jones LA; Boardman JD; Tabor J; Siegler IC...
  • Haberstick BC
  • Lessem JM
  • Hewitt JK
  • Smolen A
  • Hopfer CJ
  • Halpern CT
  • Killeya-Jones LA
  • Boardman JD
  • Tabor J
  • Siegler IC
Published in: Biological Psychiatry
Publication Date: 2014-01-01
Type: Journal Article

Quantitative trait loci that influence antisocial drug dependence in adolescence: A replication analysis

CU Boulder Authors: McQueen, Matt; Lessem, Jeffrey; Krauter, Kenneth S; Stallings, Michael C
All Authors:
Lessem J; Corley R; Stallings M; Brown S; Hewitt J; Hopfer C; Krauter K; Mikulich-Gilbertson S; McQueen M; Rhee S...
  • Lessem J
  • Corley R
  • Stallings M
  • Brown S
  • Hewitt J
  • Hopfer C
  • Krauter K
  • Mikulich-Gilbertson S
  • McQueen M
  • Rhee S
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2012-11-01
Type: Journal Article

The CHRNA5/A3/B4 Gene Cluster and Tobacco, Alcohol, Cannabis, Inhalants and Other Substance Use Initiation: Replication and New Findings Using Mixture Analyses

CU Boulder Authors: Ehringer, Marissa A; Lessem, Jeffrey; Hewitt, John K
All Authors: Lubke GH; Stephens SH; Lessem JM; Hewitt JK; Ehringer MA
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2012-07-01
Type: Journal Article

Dizziness and the genetic influences on subjective experiences to initial cigarette use

CU Boulder Authors: Lessem, Jeffrey; Ehringer, Marissa A; Hewitt, John K
All Authors: Haberstick BC; Ehringer MA; Lessem JM; Hopfer CJ; Hewitt JK
Published in: Addiction
Publication Date: 2011-02-01
Type: Journal Article

Stable Genes and Changing Environments: Body Mass Index Across Adolescence and Young Adulthood

CU Boulder Authors: Lessem, Jeffrey; Hewitt, John K; Boardman, Jason D; McQueen, Matt
All Authors: Haberstick BC; Lessem JM; McQueen MB; Boardman JD; Hopfer CJ; Smolen A; Hewitt JK
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2010-07-01
Type: Journal Article

The Association Between Conduct Problems and Maltreatment: Testing Genetic and Environmental Mediation

CU Boulder Authors: Rhee, Soo H; Hewitt, John K; Lessem, Jeffrey
All Authors: Schulz-Heik RJ; Rhee SH; Silvern LE; Haberstick BC; Hopfer C; Lessem JM; Hewitt JK
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2010-05-01
Type: Journal Article

Investigation of Genetically Mediated Child Effects on Maltreatment

CU Boulder Authors: Lessem, Jeffrey; Hewitt, John K; Rhee, Soo H
All Authors: Schulz-Heik RJ; Rhee SH; Silvern L; Lessem JM; Haberstick BC; Hopfer C; Hewitt JK
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2009-05-01
Type: Journal Article

Marijuana Use and BMI in the Add Health Sample

CU Boulder Authors: McQueen, Matt; Lessem, Jeffrey; Hewitt, John K
All Authors: Lessem JM; Haberstick BC; Hewitt JK; Hopfer CJ; McQueen MB
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2008-11-01
Type: Journal Article

Using Observed Genetic Variables to Predict Latent Class Membership: A Comparison of Two Methods

CU Boulder Authors: Lessem, Jeffrey
All Authors: Lubke G; Carey G; Lessem J; Hewitt J
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2008-11-01
Type: Journal Article

Association of candidate genes with antisocial drug dependence in adolescents

CU Boulder Authors: Hewitt, John K; Stallings, Michael C; Krauter, Kenneth S; Rhee, Soo H; McQueen, Matt; Ehringer, Marissa A; Lessem, Jeffrey
All Authors:
Corley RP; Zeiger JS; Crowley T; Ehringer MA; Hewitt JK; Hopfer CJ; Lessem J; McQueen MB; Rhee SH; Smolen A...
  • Corley RP
  • Zeiger JS
  • Crowley T
  • Ehringer MA
  • Hewitt JK
  • Hopfer CJ
  • Lessem J
  • McQueen MB
  • Rhee SH
  • Smolen A
Published in: Drug and Alcohol Dependence
Publication Date: 2008-07-01
Type: Journal Article

Genetic and environmental contributions to retrospectively reported DSM-IV childhood attention deficit hyperactivity disorder

CU Boulder Authors: Hewitt, John K; Ehringer, Marissa A; Lessem, Jeffrey
All Authors: Haberstick BC; Timberlake D; Hopfer CJ; Lessem JM; Ehringer MA; Hewitt JK
Published in: Psychological Medicine
Publication Date: 2008-07-01
Type: Journal Article

The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults

CU Boulder Authors: Lessem, Jeffrey; Rhee, Soo H; McQueen, Matt; Ehringer, Marissa A; Hewitt, John K
All Authors:
Schlaelpfer IR; Hoft NR; Collins AC; Corley RP; Hewitt JK; Hopfer CJ; Lessem JM; McQueen MB; Rhee SH; Ehringer MA...
  • Schlaelpfer IR
  • Hoft NR
  • Collins AC
  • Corley RP
  • Hewitt JK
  • Hopfer CJ
  • Lessem JM
  • McQueen MB
  • Rhee SH
  • Ehringer MA
Published in: Biological Psychiatry
Publication Date: 2008-06-01
Type: Journal Article

The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco

CU Boulder Authors: Lessem, Jeffrey; Ehringer, Marissa A; Hewitt, John K; McQueen, Matt; Rhee, Soo H
All Authors:
Zeiger JS; Haberstick BC; Schlaepfer I; Collins AC; Corley RP; Crowley TJ; Hewitt JK; Hopfer CJ; Lessem J; McQueen MB...
  • Zeiger JS
  • Haberstick BC
  • Schlaepfer I
  • Collins AC
  • Corley RP
  • Crowley TJ
  • Hewitt JK
  • Hopfer CJ
  • Lessem J
  • McQueen MB
Published in: Human Molecular Genetics
Publication Date: 2008-03-01
Type: Journal Article

Association between body mass index and MAOA genotype

CU Boulder Authors: Lessem, Jeffrey; Hewitt, John K
All Authors: Lessem JM; Haberstick BC; Hopfer CJ; Smolen A; Hewitt JK
Published in: Behavior Genetics: an international journal devoted to research in the inheritance of behavior in animals and man
Publication Date: 2007-11-01
Type: Journal Article

Pages