Wei Zhou

Date first presented

June 2021 Virtual Workshop


This is a lecture about conducting set-based association tests in large-scale biobanks and cohorts. It introduces the R package SAIGE-GENE, which was developed for conducting exome-wide or genome-wide set-based tests for rare variants in large-scale biobanks, while accounting for unbalanced case-control ratios, handling sample relatedness, and being scalable for large data sets.