Gastrointestinal Tissue Mechanics

Project Focus

Our research in GI tissue mechanics has focused on characterizing the mechanical tissue properties of the GI tract and modeling how robotic capsule endoscope interact with these tissues. These efforts have included benchtop, animal and human in vivo measurements. Outcomes from this research will help medical device designer develop more effective tools for improved procedure outcomes. Project funding and recent peer-reviewed papers are listed below.

Publications:

  1. Sliker, L.J., Ciuti, G., Rentschler, M.E., Menciassi, A., "Frictional Resistance Model for Tissue-Capsule Endoscope Sliding Contact in the Gastrointestinal Tract," Tribology International. 102: 472-484, 2016. (PDF)

  2. Francisco, M., Terry, B.S., Schoen, J.A., Rentschler, M.E., "An Intestinal Manometry Force Sensor for Robotic Capsule Endoscopy: An Acute, Multi-Patient In vivo Animal and Human Study," IEEE Transactions on Biomedical Engineering. 63(5): 943-951, 2016. (PDF)

  3. Terry, B.S., Wang, X., Schoen, J.A., Rentschler, M.E., "A Preconditioning Protocol and Biaxial Mechanical Measurement of the Small Intestine," International Journal of Experimental and Computational Biomechanics. 2(4): 293-309, 2014. (PDF)

  4. Lyle, A.B., Terry, B.S., Schoen, J.A., Rentschler, M.E., "Preliminary Friction Force Measurements on Small Bowel Lumen when Eliminating Sled Edge Effects," Tribology Letters. 51(3): 377-383, 2013.  (PDF)

  5. Wang, X., Sliker, L.J., Qi, H., Rentschler, M.E., "A Quasi-static Model of Wheel-Tissue Interaction for Surgical Robotics," Medical Engineering and Physics. 35(9): 1368-1376, 2013. (PDF)

  6. Lyle, A.B., Luftig, J.T., Rentschler, M.E., "A Tribological Investigation of the Small Bowel Lumen Surface," Tribology International. 62: 171-176, 2013. (PDF)

  7. Wang, X., Schoen, J.A., Rentschler, M.E., "A Quantitative Comparison of Soft Tissue Compressive Viscoelastic Model Accuracy," Journal of Mechanical Behavior of Biomedical Materials. 20: 126-136, 2013. (PDF)

  8. Terry, B.S., Schoen, J.A., Rentschler, M.E., "Measurements of the Contact Force from Myenteric Contractions on a Solid Bolus," Journal of Robotic Surgery. 7(1): 53-57, 2013. (PDF)

  9. Terry, B.S., Passernig, A.C., Hill, M., Schoen, J.A., Rentschler, M.E., "Small Intestine Mucusal Adhesivity to In vivo Capsule Robot Materials," Journal of Mechanical Behavior of Biomedical Materials. 15: 24-32, 2012. (PDF)

  10. Terry, B.S., Schoen, J.A., Rentschler, M.E., "Characterization and Experimental Results of a Novel Sensor for Measuring the Contact Force from Myenteric Contractions," IEEE Transactions on Biomedical Engineering. 59(7): 1971-1977, 2012. (PDF)

  11. Terry, B.S., Lyle, A., Schoen, J.A., Rentschler, M.E., "Preliminary Mechanical Characterization of the Small Bowel for In vivo Robotic Mobility," ASME Journal of Biomechanical Engineering. 133(9): 091010-1-091010-7, 2011. (PDF)

Videos:

Funding:

CCTSI
 Gastrointestinal Tract Tissue Mechanics Characterization for Mobile In vivo Surgical Robots

 CU Innovative Seed Grant