March 2023
- Dipeptidyl peptidase 4 Promotes Survival and Stemness of Acute Myeloid Leukemia Stem Cells (Cell Reports) https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00116-X
- Generation of Self-Organized Autonomic Ganglion Organoids from Fibroblasts (iScience) https://www.cell.com/iscience/fulltext/S2589-0042(23)00318-8
- Human Gene-Engineered Calreticulin Mutant Stem Cells Recapitulate MPN Hallmarks and Identify Targetable Vulnerabilities (Leukemia) https://www.nature.com/articles/s41375-023-01848-6
- Melatonin-Mediated FKBP4 Downregulation Protects against Stress-Induced Neuronal Mitochondria Dysfunctions by Blocking Nuclear Translocation of GR (Cell Death & Disease) https://www.nature.com/articles/s41419-023-05676-5
- Patient-Derived Spheroids and Patient-Derived Organoids Simulate Evolutions of Lung Cancer (Heliyon) https://www.cell.com/heliyon/fulltext/S2405-8440(23)01036-8
- Psychedelics Promote Neuroplasticity through the Activation of Intracellular 5-HT2A Receptors (Science) https://www.science.org/doi/10.1126/science.adf0435
- A Multi-Organoid Platform Identifies CIART as a Key Factor for SARS-CoV-2 Infection (Nature Cell Biology) https://www.nature.com/articles/s41556-023-01095-
- Apoptosis Inhibition Enhances Induced Pluripotent Stem Cell Generation during T Cell Reprogramming (Biochemical and Biophysical Research Communications) https://www.sciencedirect.com/science/article/pii/S0006291X23003017
- Clinical Use of CAR T-cells in Treating Acute Lymphoblastic Leukemia (Transfusion And Apheresis Science) https://www.trasci.com/article/S1473-0502(23)00034-4/fulltext
- Dying Transplanted Neural Stem Cells Mediate Survival Bystander Effects in the Injured Brain (Cell Death & Disease) https://www.nature.com/articles/s41419-023-05698-z
- Fibroblast Heterogeneity: Keystone of Tissue Homeostasis and Pathology in Inflammation and Aging (Frontiers In Immunology) https://www.frontiersin.org/articles/10.3389/fimmu.2023.1137659/full#.ZAGqpOGK99A.twitter
- Generation of Functional Oocytes from Male Mice In Vitro (Nature) https://www.nature.com/articles/s41586-023-05834-x
- Highly Efficient and Rapid Generation of Human Pluripotent Stem Cells by Chemical Reprogramming (Cell Stem Cell) https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(23)00069-3
- Improved Survival of Patients with Primary Plasma Cell Leukemia with VRd or Daratumumab-based Quadruplets: A Multicenter Study by the Greek Myeloma Study Group (American Journal Of Hematology)https://onlinelibrary.wiley.com/doi/10.1002/ajh.26891
- Implantation of Engineered Human Microvasculature to Study Human Infectious Diseases in Mouse Models (iScience) https://www.cell.com/iscience/fulltext/S2589-0042(23)00363-2
- The Novel GATA1-Interacting Protein HES6 Is an Essential Transcriptional Cofactor for Human Erythropoiesis (Nucleic Acids Research) https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad167/7079638?login=false
- Very Small Embryonic-Like Stem Cells Transform into Cancer Stem Cells and Are Novel Candidates for Detecting/Monitoring Cancer by a Simple Blood Test (Stem Cells)https://academic.oup.com/stmcls/advance-article-abstract/doi/10.1093/stmcls/sxad015/7070983?redirectedFrom=fulltext&login=false
February 2023
- A Molecular Characterization and Clinical Relevance of Microglia-Like Cells Derived from Patients with Panic Disorder (Translational Psychiatry) https://www.nature.com/articles/s41398-023-02342-4
- Bioengineering Approaches to Promote Maturity in Human Skeletal Muscle Constructs (Biophysical Journal) https://www.cell.com/biophysj/fulltext/S0006-3495(22)03260-X
- Cancer Stem Cells: Recent Insights and Therapies (Biochemical Pharmacology) https://www.sciencedirect.com/science/article/pii/S0006295223000321
- Supports Meso-Endoderm Differentiation from Mouse Embryonic Stem Cells (Nature Communications) https://www.nature.com/articles/s41467-023-35938-x
- Inflammation and DNA Damage: Cause, Effect or Both (Nature Reviews Rheumatology) https://www.nature.com/articles/s41584-022-00905-1
- iPSC-Based Modeling of THD Recapitulates Disease Phenotypes and Reveals Neuronal Malformation (EMBO Molecular Medicine) https://www.embopress.org/doi/full/10.15252/emmm.202215847
- Lnc956-TRIM28-HSP90B1 Complex on Replication Forks Promotes CMG Helicase Retention to Ensure Stem Cell Genomic Stability and Embryogenesis (Science Advances) https://www.science.org/doi/10.1126/sciadv.adf6277
- Multicenter Long-Term Follow-Up of Allogeneic Hematopoietic Cell Transplantation with Omidubicel: A Pooled Analysis of Five Prospective Clinical Trials (Transplantation And Cellular Therapy) https://www.sciencedirect.com/science/article/abs/pii/S2666636723010710?via%3Dihub
- NANOGP1, a Tandem Duplicate of NANOG, Exhibits Partial Functional Conservation in Human Naïve Pluripotent Stem Cells (Development) https://journals.biologists.com/dev/article/150/2/dev201155/286681/NANOGP1-a-tandem-duplicate-of-NANOG-exhibits
- Nanosheet Coating Improves Stability of Human Pluripotent Stem Cell Culture on Glass Substrates (Biochemical and Biophysical Research Communications) https://www.sciencedirect.com/science/article/pii/S0006291X23001080
- Reversal of Aging-Associated Increase in Myelopoiesis and Expression of Alarmins by Angiotensin-(1–7) (Scientific Reports) https://www.nature.com/articles/s41598-023-29853-w
- Transcriptional Reprogramming of Skeletal Muscle Stem Cells by the Niche Environment (Nature Communications) https://www.nature.com/articles/s41467-023-36265-x
- Transgenic Skin Biomechanical Properties Following First Lifesaving Epidermal Regeneration Using Combined Gene and Cell Therapy (Journal of the German Society of Dermatology) https://onlinelibrary.wiley.com/doi/10.1111/ddg.14978
January 2023
- Administration of Stem Cells against Cardiovascular Diseases with a Focus on Molecular Mechanisms: Current Knowledge and Prospects (Tissue and Cell) https://www.sciencedirect.com/science/article/pii/S0040816623000186
- Binary Colloidal Crystals Promote Cardiac Differentiation of Human Pluripotent Stem Cells via Nuclear Accumulation of SETDB1 (ACS Nano) https://pubs.acs.org/doi/10.1021/acsnano.3c00009
- Corneal Stem Cells Niche and Homeostasis Impacts in Regenerative Medicine; Concise Review (European Journal of Ophthalmology) https://journals.sagepub.com/doi/10.1177/11206721221150065
- Cross-Species Transcriptomic Atlas of Dorsal Root Ganglia Reveals Species-Specific Programs for Sensory Function (Nature Communications) https://www.nature.com/articles/s41467-023-36014-0
- Endothelial Cell-Derived Exosomes Boost and Maintain Repair-Related Phenotypes of Schwann Cells via miR199-5p to Promote Nerve Regeneration (Journal Of Nanobiotechnology) https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-023-01767-9
- Generation of Urine-Derived Induced Pluripotent Stem Cells and Cerebral Organoids for Modeling Down Syndrome (Stem Cell Reviews and Reports) https://link.springer.com/article/10.1007/s12015-022-10497-8
- Human iPSC-Derived Preclinical Models to Identify Toxicity of Tumor-Specific T Cells with Clinical Potential (Molecular Therapy-Methods & Clinical Development) https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329-0501(23)00007-4
- Photoreceptor Laminin Drives Differentiation of Human Pluripotent Stem Cells to Photoreceptor Progenitors That Partially Restore Retina Function (Molecular Therapy) https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(22)00716-X
- Progenitor-Derived Endothelin Controls Dermal Sheath Contraction for Hair Follicle Regression (Nature Cell Biology) https://www.nature.com/articles/s41556-022-01065-w
- Protein Kinase C Modulation Determines the Mesoderm/Extraembryonic Fate under BMP4 Induction from Human Pluripotent Stem Cells (Stem Cells) https://academic.oup.com/stmcls/advance-article-abstract/doi/10.1093/stmcls/sxad006/6989577
- The Impact of the Cellular Environment and Aging on Modeling Alzheimer’s Disease in 3D Cell Culture Models (Advanced Science) https://onlinelibrary.wiley.com/doi/10.1002/advs.202205037
- Transcriptional and Functional Effects of Lithium in Bipolar Disorder iPSC-Derived Cortical Spheroids (Molecular Psychiatry) https://www.nature.com/articles/s41380-023-01944-0
- Transplanted Human iPSC-Derived Vascular Endothelial Cells Promote Functional Recovery by Recruitment of Regulatory T Cells to Ischemic White Matter in the Brain (Journal of Neuroinflammation) https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-023-02694-0
December 2022
· RNA Degradation Eliminates Developmental Transcripts during Murine Embryonic Stem Cell Differentiation via CAPRIN1-XRN2 https://www.cell.com/developmental-cell/fulltext/S1534-5807(22)00814-0
· Embryonic Origins of Adult Pluripotent Stem Cells https://www.cell.com/cell/fulltext/S0092-8674(22)01420-9
· Bulk RNA sequencing analysis of developing human induced pluripotent cell-derived retinal organoids https://www.nature.com/articles/s41597-022-01853-x
· Effect of thymoquinone on pharmacokinetics of 5-fluorouracil in rats and its effect on human cell line in vitro https://journals.sagepub.com/doi/10.1177/09603271211021475?icid=int.sj-full-text.similar-articles.1
· Stress-Induced Reversible Cell-Cycle Arrest Requires PRC2/PRC1-Mediated Control of Mitophagy in Drosophila Germline Stem Cells and Human iPSCs https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(22)00537-9
· Plpp3, a novel regulator of pluripotency exit and endodermal differentiation of mouse embryonic stem cells https://journals.biologists.com/bio/article/12/1/bio059665/286423/Plpp3-a-novel-regulator-of-pluripotency-exit-and
· Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells https://www.nature.com/articles/s41551-022-00969-0
· CD34dim cells identified as pluripotent stem cell-derived definitive hemogenic endothelium purified using bone morphogenetic protein 4 https://onlinelibrary.wiley.com/doi/full/10.1111/cpr.13366
· A Reference Human Induced Pluripotent Stem Cell Line for Large-Scale Collaborative Studies https://www.nature.com/articles/s41467-022-35180-x
· The Consequences of Recurrent Genetic and Epigenetic Variants in Human Pluripotent Stem Cells https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(22)00453-2
· Dialysis based-culture medium conditioning improved the generation of human induced pluripotent stem cell derived-liver organoid in a high cell density https://www.nature.com/articles/s41598-022-25325-9
November 2022
- Long-Range Axonal Projections of Transplanted Mouse Embryonic Stem Cell-Derived Hypothalamic Neurons into Adult Mouse Brain (PLoS One) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0276694
- Modeling Placental Development and Disease Using Human Pluripotent Stem Cells (Placenta)https://www.sciencedirect.com/science/article/pii/S0143400422004362?via%3Dihub
- Transcription Factor Antagonism Regulates Heterogeneity in Embryonic Stem Cell States (Molecular Cell) https://www.cell.com/molecular-cell/fulltext/S1097-2765(22)01022-X
- Membrane Potential Drives the Exit from Pluripotency and Cell Fate Commitment via Calcium and mTOR (Nature Communications) https://www.nature.com/articles/s41467-022-34363-w
- Lamin A/C-dependent Chromatin Architecture Safeguards Naïve Pluripotency to Prevent Aberrant Cardiovascular Cell Fate and Function (Nature Communications) https://www.nature.com/articles/s41467-022-34366-7
- Virtual Cells in a Virtual Microenvironment Recapitulate Early Development-Like Patterns in Human Pluripotent Stem Cell Colonies (Stem Cell Reports) https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(22)00500-8
- Stabilization of hESCs in Two Distinct Substrates along the Continuum of Pluripotency (iScience) https://www.cell.com/iscience/fulltext/S2589-0042(22)01741-2
- Acute Severe Hypoxia Induces Apoptosis of Human Pluripotent Stem Cells by a HIF-1α and P53 Independent Mechanism (Scientific Reports) https://www.nature.com/articles/s41598-022-23650-7
- Intermediate Cells of In Vitro Cellular Reprogramming and In Vivo Tissue Regeneration Require Desmoplakin (Science Advances) https://www.science.org/doi/10.1126/sciadv.abk1239
- Transient Inhibition of p53 Enhances Prime Editing and Cytosine Base-Editing Efficiencies in Human Pluripotent Stem Cells (Nature Communications) https://www.nature.com/articles/s41467-022-34045-7
- Stabilization of Cell-Cell Adhesions Prevents Symmetry Breaking and Locks In Pluripotency in 3D Gastruloids (Stem Cell Reports) https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(22)00462-3
- Nucleosome Breathing Facilitates Cooperative Binding of Pluripotency Factors Sox2 and Oct4 to DNA(Biophysical Journal) https://www.cell.com/biophysj/pdf/S0006-3495(22)00893-1.pdf
- Therapeutic Function of a Novel Rat Induced Pluripotent Stem Cell Line in a 6-OHDA-Induced Rat Model of Parkinson’s Disease (International Journal of Molecular Medicine]) https://www.spandidos-publications.com/10.3892/ijmm.2022.5196
- Embryonic Stem Cells Lacking DNA Methyltransferases Differentiate into Neural Stem Cells That Are Defective in Self-Renewal (International Journal of Stem Cells)https://www.ijstemcell.com/journal/view.html?doi=10.15283/ijsc22138
- Using Pluripotent Stem Cells to Understand Normal and Leukemic Hematopoietic Development (Stem Cells Translational Medicine) https://academic.oup.com/stcltm/advance-article/doi/10.1093/stcltm/szac071/6767589?login=true
October 2022
World’s first stem cell treatment for spina bifida delivered during fetal surgery! https://health.ucdavis.edu/news/headlines/worlds-first-stem-cell-treatment-for-spina-bifida-delivered-during-fetal-surgery--/2022/10 https://ucdavis.app.box.com/s/bkou2xl5uwqee2rsc2zycjshgl98v1c5/file/1032501468464
- Identification of Stable Housekeeping Genes for Induced Pluripotent Stem Cells and -Derived Endothelial Cells for Drug Testing (Scientific Reports) https://www.nature.com/articles/s41598-022-20435-w
- TGFβ Superfamily Signaling Regulates the State of Human Stem Cell Pluripotency and Capacity to Create Well-Structured Telencephalic Organoids (Stem Cell Reports) https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(22)00422-2
- The Kleisin Subunits of Cohesin Are Involved in the Fate Determination of Embryonic Stem Cells (Molecules and Cells) https://www.molcells.org/journal/view.html?doi=10.14348/molcells.2022.2042
- Human Cellular Models for Retinal Disease: From Induced Pluripotent Stem Cells to Organoids (Retina-the Journal of Retinal and Vitreous Diseases) https://journals.lww.com/retinajournal/Abstract/2022/10000/HUMAN_CELLULA...
- Super-Enhancers Conserved within Placental Mammals Maintain Stem Cell Pluripotency (Proceedings of the National Academy of Sciences of the United States of America) https://www.pnas.org/doi/10.1073/pnas.2204716119
- High Glucose Impairs Osteogenic Differentiation of Embryonic Stem Cells via Early Diversion of Beta-Catenin from Forkhead Box O to T Cell Factor Interaction (Birth Defects Research) https://onlinelibrary.wiley.com/doi/10.1002/bdr2.2085
September 2022
- Retinoic Acid Delays Initial Photoreceptor Differentiation and Results in a Highly Structured Mature Retinal Organoid (Stem Cell Research & Therapy) https://stemcellres.biomedcentral.com/articles/10.1186/s13287-022-03146-x
- Engineering Placenta-Like Organoids Containing Endogenous Vascular Cells from Human-Induced Pluripotent Stem Cells (Bioengineering & Translational Medicine) https://aiche.onlinelibrary.wiley.com/doi/full/10.1002/btm2.10390
- Induction of Functional Xeno-Free MSCs from Human iPSCs via a Neural Crest Cell Lineage (NPJ Regenerative Medicine) https://www.nature.com/articles/s41536-022-00241-8
- CTCF Acetylation at Lysine 20 Is Required for the Early Cardiac Mesoderm Differentiation of Embryonic Stem Cells (Cell Regeneration) https://cellregeneration.springeropen.com/articles/10.1186/s13619-022-00...
- Evolutionary Origin of Vertebrate OCT4/POU5 Functions in Supporting Pluripotency (Nature Communications) https://www.nature.com/articles/s41467-022-32481-z
- Dominant Role of DNA Methylation over H3K9me3 for IAP Silencing in Endoderm (Nature Communications) https://www.nature.com/articles/s41467-022-32978-7
- LncRNA-Smad7 Mediates Cross-Talk between Nodal/TGF-β and BMP Signaling to Regulate Cell Fate Determination of Pluripotent and Multipotent Cells (Nucleic Acids Research) https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac780/671...
- Passage Number Affects Differentiation of Sensory Neurons from Human Induced Pluripotent Stem Cells (Scientific Reports) https://www.nature.com/articles/s41598-022-19018-6
- Modeling Urea Cycle Disorders Using iPSCs (NPJ Regenerative Medicine) https://www.nature.com/articles/s41536-022-00252-5
- Building In Vitro Models of the Brain To Understand the Role of APOE in Alzheimer’s Disease [Life Science Alliance] https://www.life-science-alliance.org/content/5/11/e202201542
- PFOS Disrupts Key Developmental Pathways during hiPSC Derived Cardiomyocyte Differentiation (In Vitro Toxicology in Vitro) https://www.sciencedirect.com/science/article/pii/S0887233322001734?via%...
- Imprinting Fidelity in Mouse iPSCs Depends on Sex of Donor Cell and Medium Formulation (Nature Communications) https://www.nature.com/articles/s41467-022-33013-55
- CRISPR-Cas9 Screen in Human Embryonic Stem Cells to Identify Genes Required for Neural Differentiation (STAR Protocols) https://www.sciencedirect.com/science/article/pii/S2666166722005627?via%...
- Different Transcriptional Profiles of Human Embryonic Stem Cells Grown in a Feeder-Free Culture System and on Human Foreskin Fibroblast Feeder Layers (Aging-Us) https://www.aging-us.com/article/204282/text
- Fast Generation of Forebrain Oligodendrocyte Spheroids from Human Embryonic Stem Cells by Transcription Factors (iScience) https://www.cell.com/action/showPdf?pii=S2589-0042%2822%2901444-4
- METTLing in Stem Cell and Cancer Biology (Stem Cell Reviews and Reports) https://link.springer.com/article/10.1007/s12015-022-10444-7
- A Stem Cell Roadmap of Ribosome Heterogeneity Reveals a Function for RPL10A in Mesoderm Production (Nature Communications) https://www.nature.com/articles/s41467-022-33263-3
- Human PSCs Determine the Competency of Cerebral Organoid Differentiation via FGF Signaling and Epigenetic Mechanisms (iScience) https://www.cell.com/action/showPdf?pii=S2589-0042%2822%2901412-2
- Mouse Embryo Model Derived Exclusively from Embryonic Stem Cells Undergoes Neurulation and Heart Development (Cell Stem Cell) https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(22)00377-0
- Heparinized Gelatin-Based Hydrogels for Differentiation of Induced Pluripotent Stem Cells (Biomacromolecules) https://pubs.acs.org/doi/10.1021/acs.biomac.2c00585
- Acquisition and Maintenance of Pluripotency Are Influenced by Fibroblast Growth Factor, Leukemia Inhibitory Factor, and 2i in Bovine-Induced Pluripotent Stem Cells (Frontiers in Cell and Developmental Biology) https://www.stemcellsciencenews.com/newsletter/194131/
- Recent Advances for Using Human Induced-Pluripotent Stem Cells as Pain-in-a-Dish Models of Neuropathic Pain (Experimental Neurology) https://www.sciencedirect.com/science/article/pii/S0014488622002485?via%...
- Modeling Metabolic Diseases and Drug Response Using Stem Cells and Organoids (Nature Reviews Endocrinology) https://www.nature.com/articles/s41574-022-00733-z
- Harnessing Conserved Signaling and Metabolic Pathways to Enhance the Maturation of Functional Engineered Tissues (NPJ Regenerative Medicine) https://www.nature.com/articles/s41536-022-00246-3
- Spatial Molecular Anatomy of Germ Layers in the Gastrulating Cynomolgus Monkey Embryo (Cell Reports) https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01105-6
- Modeling Human Extraembryonic Mesoderm Cells Using Naive Pluripotent Stem Cells (Cell Stem Cell) https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(22)00337-X
- Systemic Proteomics and miRNA Profile Analysis of Exosomes Derived from Human Pluripotent Stem Cells (Stem Cell Research & Therapy) https://stemcellres.biomedcentral.com/articles/10.1186/s13287-022-03142-1
- Robust Genome Editing via modRNA-Based Cas9 or Base Editor in Human Pluripotent Stem Cells (Cell Reports Methods) https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(22)00172-2
- Molecular Convergence between Down Syndrome and Fragile X Syndrome Identified Using Human Pluripotent Stem Cell Models (Cell Reports) https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01136-6
- Modeling Human Multi-Lineage Heart Field Development with Pluripotent Stem Cells (Cell Stem Cell) https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(22)00343-5
- Generation of Human Induced Pluripotential Stem Cells from Individuals with Complex Heterozygous, Isogenic Corrected, and Homozygous Bloc1s1 Mutations (Stem Cell Research) https://www.sciencedirect.com/science/article/pii/S1873506122002549
August 2022
- DLL4 and VCAM1 Enhance the Emergence of T Cell–Competent Hematopoietic Progenitors from Human Pluripotent Stem Cells (Science Advances) https://www.science.org/doi/10.1126/sciadv.abn5522
- Repeated Intravenous Administration of hiPSC-MSCs Enhance the Efficacy of Cell-Based Therapy in Tissue Regeneration (Communications Biology) https://www.nature.com/articles/s42003-022-03833-8