New broad-spectrum antiviral protein can inhibit HIV, other pathogens in some primates

Jan. 18, 2017

University of Colorado Boulder researchers have discovered that a protein-coding gene called Schlafen11 (SLFN11) may induce a broad-spectrum cellular response against infection by viruses including HIV-1. The new research, which was recently published in the journal PLOS Pathogens , found that SLFN11's antiviral potency is highest in non-human primate species...

Loren Hough

Scientist develops a new way to look at a cellular shapeshifter

Oct. 21, 2016

Tubulin, a protein found in your cells, quietly lends itself to many life processes. It sorts itself into long chains, forming tubes that provide scaffolding for living cells. A versatile shapeshifter, tubulin can arrange itself into different structures during different types of cell behavior. Tubulin gained prominence for medical applications...

Tom Cech's lab is focused, in part, on studying telomerase: a powerful enzyme found at the ends of chromosomes.

Live Cells reveal cancer process

Aug. 11, 2016

A deep look inside the live cells reveals a key cancer process Telomerase, a powerful enzyme found at the ends of chromosomes, can keep humans healthy, or promote cancer growth. Researchers at the University of Colorado in Boulder used a process called single-molecule imaging to look into the complicated processes...

BioFrontiers' Aaron Clauset used computer networking techniques to better understand malaria's genetic strategy.

Tracking malaria's evolution

Oct. 12, 2015

A new paper published Nature Communications , coauthored by a researcher at the University of Colorado’s BioFrontiers Institute, looked at the genetic strategy used by the human malaria parasite and how old it is from an evolutionary perspective. BioFrontiers’ Aaron Clauset, an assistant professor of computer science, was part of...

Sara Sawyer recently joined BioFrontiers. Now that the dust is settling in her lab, she's back to focusing on zoonotic diseases.

Using evolution to fight disease

June 25, 2015

New BioFrontiers lab uses evolution to fight disease by Paul McDivitt Photo: Sara Sawyer Ebola comes from bats, HIV from primates, and new strains of influenza from birds and pigs. With zoonotic diseases – those capable of transmission from animals to humans – grabbing headlines across the globe, understanding how...

BioFrontiers Hubert Yin is focused on toll-like receptors that may play a role in new therapies for neurodegenerative diseases.

Finding a new strategy for Parkinson's

May 12, 2015

If you believe the common adage that you are only using ten percent of your brain, while the other ninety percent remains untapped potential, you are about to be surprised. It’s true that about ten percent of your nervous system is made up of hard-working neurons, diligently delivering messages back...

BioFrontiers Hubert Yin is focused on toll-like receptors that may play a role in new cancer therapies.

Unlocking toll-like receptors

April 10, 2015

BioFrontiers’ Hubert Yin is unlocking the power of toll-like receptors Hubert Yin has been thinking about one type of cell receptor since he joined the BioFrontiers Institute, and it is a receptor worthy of that kind of time. Yin, an Associate Professor of Chemistry and Biochemistry, is focusing much of...

Telomeres sit at the ends of chromosomes to protect their genetic data (colorful DNA pic) Credit: Jane Ades, NHGRI

Research on small cellular changes may lead to big cancer solutions

March 10, 2015

Among cancers, scientists have spent their entire research careers looking for cellular similarities that may lead to a single cure for many cancers –– the rare chance to have a single answer to a multifaceted problem. In 1997, scientists discovered a gene that they believed was the key to cellular...

BioFrontiers' Amy Palmer studies the effects that zinc has on a wide variety of cellular processes.

Amy Palmer wins NIH Pioneer Award

Oct. 9, 2014

Few people think of metals as being vital to our health. Although most people are aware of iron, zinc is just as important, and is involved in a much wider array of biological functions. Ten percent of the proteins used to build our cells, tissues and genes are predicted to...


BioFrontiers launches Sie Post-doctoral Fellowship Program

July 10, 2014

Research will focus on improving the lives of people with Down syndrome The BioFrontiers Institute at the University of Colorado launched its inaugural Sie Post-doctoral Fellowship Program in affiliation with the Linda Crnic Institute for Down Syndrome on the Anschutz Medical Campus. The program will fund three post-doctoral researchers, Sie...