Stephen Kissler
- Assistant Professor
- COMPUTER SCIENCE
Research interests
Pandemic preparedness and response
Our research group builds mathematical disease transmission models to analyze historical outbreaks and anticipate future threats. We build capacity for integrating novel data streams, like proximity sensing data from mobile phones, into outbreak surveillance and response platforms using robust, privacy-preserving approaches. We develop digital tools to guide optimal surveillance strategies when resources (e.g., testing and sequencing) must be shared across pathogens, and we seek to improve epidemic forecasts by critically evaluating the competitive dynamics of outbreak forecasting hubs.
Respiratory viral kinetics
The kinetics of viral abundance during acute respiratory infections can dictate the timing and level of a person’s contagiousness. We build statistical frameworks for extracting key features from quantitative viral abundance data (e.g., from serially administered quantitative PCR tests) and integrate these into mathematical models of disease transmission. We also build protocols for optimal viral kinetic study design.
Cross-sector impacts of epidemics
Epidemics can have far-reaching ramifications beyond the public health sphere. We develop models to assess how outbreaks may impact the food system by causing illness among essential workers, and we are designing strategies for enhanced surveillance and response to protect the food system during future outbreaks. We work closely with economists to incorporate human behavior into epidemiological models and to guide policy responses that are informed by notions of well-being that extend beyond disease-related morbidity and mortality.
Select publications
Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period
SM Kissler, C Tedijanto, E Goldstein, YH Grad, M Lipsitch
Science 368 (6493), 860-868
Viral dynamics of SARS-CoV-2 variants in vaccinated and unvaccinated persons
SM Kissler, JR Fauver, C Mack, et al.
New England Journal of Medicine 385 (26), 2489-2491
SM Kissler, N Kishore, M Prabhu, et al.
Nature communications 11 (1), 4674
Geographic transmission hubs of the 2009 influenza pandemic in the United States
SM Kissler, JR Gog, C Viboud, et al.
Epidemics 26, 86-94
SM Kissler, RM Klevens, ML Barnett, YH Grad
Clinical Infectious Diseases 72 (9), 1568-1576
SM Kissler, C Viboud, BT Grenfell, JR Gog
Journal of The Royal Society Interface 17 (164), 20190628
SM Kissler, RM Klevens, ML Barnett, YH Grad
The Journal of Infectious Diseases 223 (12), 2029-2037
Anticipating racial/ethnic mortality displacement from COVID-19
SM Kissler, YH Grad
American Journal of Epidemiology 191 (8), 1519-1520
Select awards
- NOMIS & Science Young Explorer Award
- Barry R. and Irene Tilenius Bloom Postdoctoral Fellowship
- Gates Cambridge Scholarship