John Rinn Portrait
Professor • Leslie Orgel Professor of RNA Science • Marvin H. Caruthers Endowed Chair for Early-Career Faculty
Biochemistry

Our research bridges computational and experimental sciences to discover new regulatory aspects in the human genome - - Specifically how long noncoding RNA (lncRNA) genes regulate numerous biological processes. We have continually applied and developed many technologies such as single-molecule RNA imaging, RNA-sequencing, Single Cell RNA-sequencing, CRISPR-Display and SNP-CLING. This multifaceted and cross-disciplinary approach is focused on unraveling the molecular modalities underlying RNA biology and in turn how it regulates cell state.

Latest Publications

Our teaching of Biochemistry Undergraduate and Graduate Students aims to enable all students to perform bioinformatic and data science analyses on ever emerging forms of genome-wide data such as RNA-seq, ChIP-seq, ATAC-seq.

Latest Teaching

  • 2020 - Web of Science top 1% most influential scientists in the world over the past decade.
  • 2016 - HHMI Faculty Scholars 2014 - Thompson Reuters Most Influential Scientist
  • 2014 - National Academy of Science Distinctive Voices
  • 2014 - National Academy of Science Sackler Colloquium
  • 2013 - Alvin and Esta Starr Associate Professorship
  • 2012 - PopTech Science Fellow
  • 2010 - Merkin Next Generation Fellow
  • 2009 - Damon Runyon-Rachleff Innovation
  • 2009 - NIH Innovator
  • 2009 - Popular Science Magazine’s “Brilliant 10”
  • 2008 - Smith Family Foundation Fellowship
  • 2005 - Damon Runyon Cancer Foundation Fellowship
  • 2004 - Yale University School of Arts and Sciences Commencement Marshall
  • 2003 - McDougal Fellowship, Yale University, for Professional Development.
  • 2002 - AAAS Biovision Fellowship.
  • 1999 - Department of Chemistry Honors : Awarded to top 10 chemistry graduates.
  • 1999 - Casmir Illunda Award : best senior thesis research and presentation.