Identification of the conserved phospho-acceptor site T62 in HPV-16 L2 capsid protein using mass spectrometry analysis.

Phosphorylation of Human Papillomavirus Type 16 L2 Contributes to Efficient Virus Infectious Entry

Oct. 23, 2019

The human papillomavirus (HPV) capsid comprises two viral proteins, L1 and L2, with the L2 component being essential to ensure efficient endocytic transport of incoming viral genomes. Several studies have previously reported that L1 and L2 are posttranslationally modified, but it is uncertain whether these modifications affect HPV infectious entry...

Cellular DNA damage repair proteins localize to viral replication centers.

Viral replication centers and the DNA damage response in JC virus-infected cells.

Oct. 23, 2019

JCV is a human polyomavirus (PyV) that establishes a persistent infection in its host. Current immunomodulatory therapies, such as Natalizumab for multiple sclerosis, can result in JCV reactivation, leading to the debilitating brain disease progressive multifocal leukoencephalopathy (PML). JCV is among the viruses that recruit and modulate the host DNA...

Bob Garcea

$1.1 million grant funds CU Boulder research into next-generation vaccines

Nov. 4, 2016

The University of Colorado Boulder has received a $1.1 million grant from the Bill & Melinda Gates Foundation to develop next-generation vaccines that require no refrigeration and defend against infectious diseases with just one shot. If successful, those advancements could radically transform the difficult task of dispensing life-saving immunizations in...

Hubert Yin is one of three BioFrontiers scientists who received state grants to enable commercialization.

BioFrontiers Faculty Receive BDEG Grants

June 7, 2012

BioFrontiers faculty receive commercialization grants from the State of Colorado Ten CU research projects were recently selected to receive grants through Colorado’s Bioscience Discovery Evaluation Grant Program (BDEG-Co). The State of Colorado Office of Economic Development and International Trade began the BDEG program in 2007, providing proof-of-concept grants to move...