Biomaterials

The Anseth Lab designs innovative biomaterials with programmed, tunable properties and are pioneers in stem cell and organoid technologies. Their engineered cell-material constructs have applications from understanding development and disease to tissue replacement and regeneration.

The Bryant Lab engineers 3D printed biomimetic and bioactive gels for tissue repair and regeneration with a special focus on solutions for cartilage loss or damage.

The Burdick Biomaterials and Biofabrication Lab designs new biomaterials and biofabrication technologies for lab-created microtissues that model health and disease and for clinical use. They are leaders in developing self-healing, injectable gels whose uses range from drug delivery to tissue patching, such as heart attack damage.

The Calve Musculoskeletal Extracellular Matrix Lab characterizes the material properties of assembling tissues to establish design parameters for regenerative therapies. They are particularly interested in the composition and spatial organization of the extracellular matrix, its influence on muscle mechanical properties, and the application of hyaluronic acid to muscle repair and...

The Ferguson Biomechanics and Biomimetic Lab studies how the microstructure, composition, and material properties of tissues influence mechanical behavior. Further, they examine how these properties change with disrupted mechanical loading, aging, or disease.

The Lynch Lab studies the skeletal mechanical environment and its regulation of cancer using mechanical loading model systems to correlate cellular function with cancer pathogenesis, tissue-level changes in tumor burden, and skeletal tissue strength. They aim to identify targets for treating and preventing bone metastases as well as cancer-associated reductions...