Lecture and discussion of current research in signal transduction, emphasizing molecular biology, biochemistry and genetics, including receptors, signaling pathways, control of transcription, DNA replication, mitosis, and cell cycle progression.
Students in the program take two formal courses, three credits each, of which one must be CHEM 5801 (see above). Additional electives listed are of particular interest to students in the program.
Lecture course emphasizing application of chemical techniques and tools to the interdisciplinary study of molecules in living systems.
Journal club for review of literature in signal transduction, transcription, cell cycle progression, and cell differentiation.
Course planned for Spring 2016, with training in interdisciplinary research in mathematics, computer science and biology, with problems in genomics and metagenomics.
MCDB 5312 (3+1 credits): Quantitative Optical Imaging
This class explores the fundamentals of optical imaging in biology. Covered topics include an introduction to optics and microscopes, fluorescence microscopy, and an introduction to image analysis and coding in MATLAB.
Course covers the fundamentals of stem cell biology, including properties of stem cells, technology used to identify and study stem cells, current controversies and future directions in stem cell research.
CHEM 5771 (5 credits): Advanced General Biochemistry 1 (Biochemistry CORE)
Lecture/discussion on fundamentals of protein and nucleic acid structure, purification, folding, thermodynamics and biophysical methods for measurement. (Elective for MCDB majors in the program students)
Lecture and discussion of cell regulation, including transcription, replication, chromatin structure and modulation, cell cycle regulation, and cell-cell communication. (Elective for MCDB majors students)
Lecture and discussion of cellular structure and ultrastructure, methods in microscopy and structure determination, with focus on literature review and critical analysis. (Elective for Biochemistry majors in the programstudents)
Lecture and discussion of gene regulation and expression, examined by genetics and molecular, cellular and developmental biology, including DNA structure/function, RNA, regulatory proteins, human genetic diseases and gene therapy. (Elective for Biochemistry majorsstudents)