**The 2018 deadline for this opportunity has passed or the internal application slot has been granted. Updated information will be posted when the next funding cycle opens.**
This funding opportunity announcement (FOA) is designed to support highly integrated research teams of three to six PD/PIs to address ambitious and challenging research questions that are important for the mission of NIGMS and are beyond the scope of one or two investigators. Collaborative program teams are expected to accomplish goals that require considerable synergy and managed team interactions. Project goals should not be achievable with a collection of individual efforts or projects. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields.
Applications that are mainly focused on the creation, expansion, and/or maintenance of community resources, creation of new technologies or infrastructure development are not appropriate for this FOA. Clinical trials are not allowed with this program.
CU Internal Deadline: 11:59pm MST March 29, 2018
NIH Letter of Intent Deadline: 5:00pm MST April 25, 2018
NIH Application Deadline: 5:00pm MST May 25, 2018
Internal Application Requirements (all in PDF format)
- Up to 2-page research program: proposed research should be presented as an integrated scientific program with a single set of specific aims organized to address the overall objectives rather than individual PD/PI contributions. The applicant should fully describe the biomedical problem being addressed, its significance within the relevant scientific field(s) and how successful accomplishment of the goals would provide substantial scientific advances.
- Up to 1-page team management plan: overall team management plan that addresses how the entire group will function to accomplish program objectives and vision (e.g., the appropriate organizational structure and team composition; shared leadership, contributions and distributed responsibility for decision making, resource allocation, plans for professional development, conflict resolution).
- Up to 1-page budget overview: a basic budget outlining project costs is sufficient; detailed OCG budgets are not required.
To access the online application, visit: https://colorado.secure-platform.com/a/solicitations/home/4172
For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF424 (R&R) Application Guide.
The application is required to be submitted as a multiple PD/PI application, with a minimum of 3 and a maximum of 6 PD/PIs. Visit the multiple PD/PI Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF424 (R&R) Application Guide, and the Grant Policy Statement on Multiple Principal Investigators. Minimum allowed efforts by the PD/PIs are described in the R&R Budget instructions in Part 2. Section IV.2.
Any scientists with the interest and ability to develop a team science program to address an important research question is welcome to apply. NIGMS encourages the participation of junior, early, and mid-career investigators as part of the multiple PD/PI team, with advising as appropriate. ESIs and new investigators who participate as PD/PIs will lose their early stage status for future NIH applications, but ESI leads of pilot studies will not lose ESI status. PD/PIs who have an active NIGMS R35 award can participate as PD/PIs as part of the 51% effort on their current R35 award but may not receive additional funds from this award. Applicants with substantial unrestricted research support may receive funding from this award as their one NIGMS grant award, or may participate in an unfunded advisory or consulting role without loss of their ability to receive one funded NIGMS grant, consistent with NIGMS policies.
Limited Submission Guidelines
Only one application per institution per review cycle is allowed.
Award Information and Duration
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. NIGMS anticipates supporting no more than 4-6 awards, corresponding to a total of $10,000,000 (total costs), for fiscal year 2019. Future year amounts will depend on annual appropriations and Institute priorities.
While applications may request research program budgets of up to $1.5 million direct costs per year, it is anticipated that most awards will be between $700,000-$900,000 direct costs. Inflationary adjustments are not allowed. The requested budget should be consistent with the number of PDs/PIs and the complexity and needs of the proposed program. In addition to the research program budget, an additional $250,000 direct costs per year may be requested for optional exploratory pilot studies for ESIs.
Applications may request up to five years of support.