1.7—Unlocking Mitochondrial Health: Therapeutic Potential of Bacterial Muropeptides

This technology is based on the discovery that bacterial muropeptides—small fragments of bacterial cell walls—can boost mitochondrial function and reduce cellular stress in mammals by promoting oxidative phosphorylation (OXPHOS). These naturally derived molecules act as signaling agents that enhance energy production and support mitochondrial health, opening new therapeutic avenues for metabolic, neurodegenerative, and age-related diseases. The platform offers a novel class of drug candidates rooted in host-microbe communication. With strong in vivo data and expanding IP, this is a unique opportunity to develop first-in-class mitochondrial therapeutics.

Inventor: Min Han (CU Boulder Molecular, Cellular & Developmental Biology)

Potential Applications: Health and Wellness, Biotech, Therapeutics