Mass spectrometers have low detection limits; however, the ionization of analytes may be suppressed by contaminants (including common buffer salts and detergents) present in samples. Many commonly used reagents especially for biological samples have poor compatibility with mass spectrometric ionization techniques. Additionally, the mass spectrometer can be contaminated or clogged if crude samples containing non-volatile components are introduced into the instrument.
Consequently, sample preparation is a critical component of a mass spectrometric analysis and directly relates to the quality of data the instruments can realize.
Any questions you may have regarding sample preparation, data interpretation, or method of analysis are welcome, especially if the amount of sample is limited or you require special sample handling.
If you wish to submit samples to the mass spectrometry laboratory for analysis, please follow the guidelines for each mass spectrometry technique listed below.
Any questions you may have regarding sample preparation, data interpretation, or method of analysis are welcome. We are happy to help you during the experimental design of your project in order to maximize the information resulting from our MS analysis.