2019
L.D. Amer, L.S. Saleh, C. Walker, S. Thomas, W.J. Janssen, S. Alper, S.J. Bryant. Inflammation via myeloid differentiation primary response gene 88 signaling mediates the fibrotic response to implantable synthetic poly (ethylene glycol) hydrogels. Acta biomaterialia. (2019)
Y. Yu, F. Rodriguez-Fontan, K. Eckstein, A. Muralidharan, A.C. Uzcategui, J.R. Fuchs, S. Weatherford, C.B. Erickson, S.J. Bryant, V.L. Ferguson, N.H. Miller, G. Li, K.A. Payne. Rabbit Model of Physeal Injury for the Evaluation of Regenerative Medicine Approaches. Tissue Engineering Part C: Methods. (2019).
S.J. Bryant. Synthetic Hydrogels and Implications of Immune Responses in the Context of Tissue Engineering. 2019 AIChE Annual Meeting. (2019).
A. Muralidharan, A.C. Uzcategui, R.R. McLeod, S.J. Bryant. Stereolithographic 3D Printing for Deterministic Control over Integration in Dual‐Material Composites. Advanced materials technologies. (2019).
D. Faulón Marruecos, L.S. Saleh, H.H. Kim, S.J. Bryant, D.K. Schwartz, J.L. Kaar. Stabilization of fibronectin by random copolymer brushes inhibits macrophage activation. ACS Applied Bio Materials (2019).
C. Pascual-Garrido, F. Rodriguez-Fontan, M. Haneda, E. Aisenbrey, K. Payne, J.D. Kisiday, S. Bryant. L.J. Goodrich. Mesenchymal Stem Cells Delivered in a Novel Cartilage Mimetic Hydrogel for the Treatment of Focal Chondral Lesions in an Equine Animal Model. Orthopaedic Journal of Sports Medicine (2019).
M.C. Schneider, S. Chu, M.A. Randolph, S.J. Bryant. An In Vitro and In Vivo Comparison of Cartilage Growth in Chondrocyte-Laden MMP-Sensitive Poly(Ethylene Glycol) Hydrogels with Localized TGFβ3. Acta Biomaterialia (2019).
E.A. Aisenbrey, A.A. Tomaschke, S.A .Schoonraad, K.M. Fischenich, J.A. Wahlquist, M.A. Randolph, V.L. Ferguson, S.J. Bryant. Assessment and prevention of cartilage degeneration surrounding a focal chondral defect in the porcine model. Biochemical and biophysical research communications. (2019).
A.H. Aziz, K. Eckstein, V.L. Ferguson, S.J. Bryant. The effects of dynamic compressive loading on human mesenchymal stem cell osteogenesis in the stiff layer of a bilayer hydrogel. Journal of Tissue Engineering and Regenerative Medicine (2019).
A.H. Aziz and S.J. Bryant. A comparison of hMSC osteogenesis in PEG hydrogels as a function of MMP-sensitive crosslinker and crosslink density in chemically defined medium. Biotechnology and Bioengineering (2019).
C. Pascual-Garrido, E.A. Aisenbrey, F. Rodriguez-Fontan, K.A. Payne, S.J. Bryant, L.R. Goodrich. Photo-polymerizable Injectable Cartilage Mimetic Hydrogel for the Treatment of Focal Chondral Lesions: A proof of Concept in a Rabbit Animal Model. The American Journal of Sports Medicine (2019).
E.A. Aisenbrey and S.J. Bryant. The role of chondroitin sulfate in regulating hypertrophy during MSC chondrogenesis in a cartilage mimetic hydrogel under dynamic loading. Biomaterials (2019).
2018
A.C. Uzcategui, A. Muralidharan, V.L. Ferguson, S.J. Bryant, R.R McLeod. Understanding and Improving Mechanical Properties in 3D Printed Parts using a Dual-Cure Acrylate-Based Resin for Stereolithography. Advanced Engineered Materials (2018)
Y. Ding, X. Xu, S. Sharma, M. Floren, K. Stenmark, S.J. Bryant, C.P. Neu, W. Tan. Biomimetic soft fibrous hydrogels for contractile and pharmacologically responsive smooth muscle. Acta Biomaterialia. (2018)
L.S. Saleh, S.J. Bryant. In vitro and in vivo models for assessing the host response to biomaterials. Drug Discovery Today: Disease Models. (2018)
D. Patel, S. Sharma, H.R.C. Screen, S.J. Bryant. Effects of cell adhesion motif, fiber stiffness, and cyclic strain on tenocyte gene expression in a tendon mimetic fiber composite hydrogel. Biochemical and Biophysical Research Communications. (2018)
Y. Ding, X. Xu, S. Sharma, M. Floren, K. Stenmark, S.J. Bryant, C.P. Neu, W. Tan. Biomimetic soft fibrous hydrogels for contractile and pharmacologically responsive smooth muscle. Acta Biomaterialia. (2018)
M. Carles-Carner, L.S. Saleh, S.J. Bryant. The effects of hydroxyapatite nanoparticles embedded in a MMP-sensitive photoclickable PEG hydrogel on encapsulated MC3T3-E1 pre-osteoblasts. Biomedical Materials. (2018)
L.E. Jansen, L.D. Amer, E.Y.T. Chen, T.V. Nguyen, L.S. Saleh, T. Emrick, W.F. Liu, S.J. Bryant, S.R. Peyton. Zwitterionic PEG-PC hydrogels modulate the foreign body response in a modulus-dependent manner. Biomacromolecules. (2018)
A.J. Anderson, E.B. Peters, A. Neumann, J. Wagner, B. Fairbanks, S.J. Bryant, C.N. Bowman. Cytocompatibility and Cellular Internalization of PEGylated “Clickable” Nucleic Acid Oligomers. Biomacromolecules. (2018)
L.S. Saleh, M. Carles-Carner, S.J. Bryant. The in vitro effects of macrophages on the osteogenic capabilities of MC3T3-E1 cells encapsulated in a biomimetic poly (ethylene glycol) hydrogel. Acta Biomaterialia. (2018)
N. Shaw, C. Erickson, S.J. Bryant, V.L. Ferguson, M.D. Krebs, N. Hadley-Miller, K.A. Payne. Regenerative Medicine Approaches for the Treatment of Pediatric Physeal Injuries. Tissue Engineering Part B: Reviews. (2018)
L.S. Saleh, S.J. Bryant. The Host Response in Tissue Engineering: Crosstalk Between Immune cells and Cell-laden Scaffolds. Current Opinion in Biomedical Engineering. (2018)
E.A. Aisenbrey, S.J. Bryant. A MMP7‐sensitive photoclickable biomimetic hydrogel for MSC encapsulation towards engineering human cartilage. Journal of Biomedical Materials Research Part A. (2018)
E.A. Aisenbrey, A. Tomaschke, E. Kleinjan, A. Muralidharan, C. Pascual-Garrido, R.R. McLeod, V.L. Ferguson, S.J. Bryant. A Stereolithography‐Based 3D Printed Hybrid Scaffold for In Situ Cartilage Defect Repair. Macromolecular Bioscience. (2018)
S.J. Bryant, F.J. Vernerey. Programmable Hydrogels for Cell Encapsulation and Neo‐Tissue Growth to Enable Personalized Tissue Engineering. Advanced Healthcare Materials. (2018)
C. Pascual‐Garrido, F. Rodriguez‐Fontan, E.A. Aisenbrey, K.A. Payne, J. Chahla, L.R. Goodrich, S.J. Bryant. Current and novel injectable hydrogels to treat focal chondral lesions: Properties and applicability. Journal of Orthopaedic Research. (2018)
2017
J.A. Wahlquist, F.W. DelRio, M.A. Randolph, A.H. Aziz, C.M. Heveran, S.J. Bryant, C.P. Neu, V.L. Ferguson. Indentation mapping revealed poroelastic, but not viscoelastic, properties spanning native zonal articular cartilage. Acta Biomaterialia. (2017)
S. Sharma, M. Floren, Y. Ding, K.R. Stenmark, W. Tan, S.J. Bryant. A photoclickable peptide microarray platform for facile and rapid screening of 3-D tissue microenvironments. Biomaterials. (2017)
M.C. Schneider, C.A. Barnes, S.J. Bryant. Characterization of the chondrocyte secretome in photoclickable poly (ethylene glycol) hydrogels. Biotechnology and Bioengineering. (2017)
M.C. Schneider, S. Chu, S.L. Sridhar, G. De Roucy, F.J. Vernerey, S.J. Bryant. Local Heterogeneities Improve Matrix Connectivity in Degradable and Photoclickable Poly (ethylene glycol) Hydrogels for Applications in Tissue Engineering. ACS Biomaterials Science & Engineering. (2017)
S. Chu, S.L. Sridhar, U. Akalp, S.C. Skaalure, F.J. Vernerey, S.J. Bryant. Understanding the Spatiotemporal Degradation Behavior of Aggrecanase-Sensitive Poly (ethylene glycol) Hydrogels for Use in Cartilage Tissue Engineering. Tissue Engineering Part A. (2017)
C Pascual-Garrido, FR Fontan, J Chahla, K Payne, E Aisenbrey, S.J. Bryant, R.F. LaPrade, J.C. Clohisy, L.R. Goodrich. Cartilage Repair with Mesenchymal Stem Cells (MSCs) Delivered in a Novel Chondroitin Sulfate/Polyethylene Glycol Hydrogel in a Rabbit Animal Model. Orthopaedic Journal of Sports Medicine. (2017).
D. Patel, S. Sharma, S.J. Bryant, and H.R.C. Screen. Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response. Advanced Healthcare Materials. (2017)
U. Akalp, C. Schnatwinkel, M.P. Stoykovich, S.J. Bryant, F.J. Vernerey. Structural Modeling of Mechanosensitivity in Non-Muscle Cells: Multiscale Approach to Understand Cell Sensing. ACS Biomaterials Science and Engineering. (2017)
S.L. Sridhar, M.C. Schneider, S. Chu, G. de Roucy, S.J. Bryant, F.J. Vernerey. Heterogeneity is key to hydrogel-based cartilage tissue regeneration. Soft Matter. (2017)
A.H. Aziz, J. Wahlquist, A. Sollner, V. Ferguson, F.W. DelRio, S.J. Bryant. Mechanical characterization of sequentially layered photo-clickable thiol-ene hydrogels. Journal of the Mechanical Behavior of Biomedical Materials. (2017)
2016
C.I. Fiedler, E.A. Aisenbrey, J.A. Wahlquist, V.L. Ferguson, S.J. Bryant, and R.R. McLeod. Enhanced mechanical properties of photo-clickable thiol-ene PEG hydrogels through repeated photopolymerization of in-swollen macromer. Soft Matter. (2016).
A.H. Aziz, J. Wahlquist, A. Sollner, V.L. Ferguson, F.W. DelRio, and S.J. Bryant. Mechanical characterization of sequentially layered photoclickable thiol-ene hydrogels. Journal of Mechanical Behavior of Biomedical Materials. (2016)
U. Akalp, S.J. Bryant, and F.J. Vernerey. Tuning tissue growth with scaffold degradation in enzyme-sensitive hydrogels: a Mathematical Model. Soft Matter. (2016)
L.D. Amer and S.J. Bryant. The in vitro and in vivo response to MMP-sensitive poly(ethylene glycol) hydrogels. Annals of Biomedical Engineering. (2016)
E.A. Aisenbrey and S.J. Bryant. Mechanical loading inhibits hypertrophy in chondrogenically differentiating hMSCs within a biomimetic hydrogel. Journal of Materials Chemistry Part B. (2016)
A. Neumann, T. Quinn, and S.J. Bryant. Nondestructive evaluation of a new hydrolytically degradable and photo-clickable PEG hydrogel for cartilage tissue engineering. Acta Biomaterialia. (2016)
S.C. Skaalure, U. Akalp, F. Vernerey, S.J. Bryant. Tuning Reaction and Diffusion Mediated Degradation of Enzyme-Sensitive Hydrogels. Advanced Healthcare Materials. (2016)
2015
Kinneberg KRC, Stender ME, Nelson A, Aziz AH, Mozdzen LC, Harley BAC, Bryant SJ, and Ferguson VL. Reinforcement of mono- and bi-layer poly(ethylene glycol) hydrogels with a fibrous collagen scaffold. Annals of Biomedical Engineering. (2015)
Steinmetz NJ, Aisenbrey EA, Westbrook KK, Qi HJ, Bryant SJ. Mechanical loading regulates human MSC differentiation in a multi-layer hydrogel for osteochondral tissue engineering. Acta Biomater. 21:142-53 (2015).
Akalp U., Chu S., Skaalure S.C., Bryant S.J., Doostan A., and Vernerey F.J. Determination of the Polymer-Solvent Interaction Parameter for PEG Hydrogels in Water: Application of a Self Learning Algorithm. Polymer. 1;66:135-147 (2015).
Swartzlander MD, Blakney AK, Amer LD, Hankenson KD, Kyriakides TR, Bryant SJ. Immunomodulation by mesenchymal stem cells combats the foreign body response to cell-laden synthetic hydrogels. Biomaterials. 41:79-88 (2015).
Swartzlander MD, Barnes CA, Blakney AK, Kaar JL, Kyriakides TR, Bryant SJ. Linking the foreign body response and protein adsorption to PEG-based hydrogels using proteomics. Biomaterials. 41:26-36 (2015).
Skaalure SC, Chu S, Bryant SJ. An enzyme-sensitive PEG hydrogel based on aggrecan catabolism for cartilage tissue engineering. Adv Healthc Mater. 4(3):420-31 (2015).
Amer LD, Holtzinger A, Keller G, Mahoney MJ, Bryant SJ. Enzymatically degradable poly(ethylene glycol) hydrogels for the 3D culture and release of human embryonic stem cell derived pancreatic precursor cell aggregates. Acta Biomater. 22:103-10 (2015).
Sircar S., Aisenbrey E., Bryant S.J., and Bortz D.M. Determining equilibrium osmolarity in Poly(ethylene glycol)/Chondroitin sulfate gels mimicking articular cartilage. Journal of Theoretical Biology. 7:364:397-406 (2015).
Skaalure S.C., Radhakrishnan S., and Bryant S.J. Physiological osmolarities do not enhance long-term tissue synthesis in chondrocyte-laden degradable PEG hydrogels. Journal of Biomedical Materials Research Part A. 103(6):2186-92 (2015).
2014
Farnsworth NL, Mead BE, Antunez LR, Palmer AE, Bryant SJ. Ionic osmolytes and intracellular calcium regulate tissue production in chondrocytes cultured in a 3D charged hydrogel. Matrix Biololgy. 40:17-26 (2014).
Skaalure S.C., Dimson S.O., Pennington A.M., Bryant S.J. Semi-interpenetrating networks of hyaluronic acid in degradable hydrogels for cartilage tissue engineering. Acta Biomaterialia. 10(8):3409-20 (2014).
Roberts J.J., Elder R.M., Neumann A., Jayaraman A. , Bryant S.J. Interaction of hyaluronan binding peptides with glycosaminoglycans in poly(ethylene glycol) hydrogels. Biomacromolecules. 15(4): 1132-41 (2014).
Amer L.D., Mahoney M.J., and Bryant S.J. Tissue Engineering Approaches to Cell Based Diabetes Therapy. Tissue Engineering Part B Rev. 20(5):455-67 (2014).
2013
Swartzlander MD, Lynn AD, Blakney AK, Kyriakides TR, Bryant SJ. Understanding the host response to cell-laden poly(ethylene glycol)-based hydrogels. Biomaterials. 34(4):952-64 (2013).
Roberts JJ, Bryant SJ. Comparison of photopolymerizable thiol-ene PEG and acrylate-based PEG hydrogels for cartilage development. Biomaterials. 34(38):9969-79 (2013).
Dhote V, Skaalure S, Akalp U, Roberts J, Bryant SJ, Vernerey FJ. On the role of hydrogel structure and degradation in controlling the transport of cell-secreted matrix molecules for engineered cartilage. Journal of the Mechanical Behavior of Biomedical Materials. 19:61-74 (2013).
Linnenberger A., Bodine M.I., Fiedler C., Roberts J.J., Skaalure S.C., Quinn J.P., Bryant S.J., Cole M., and McLeod R.R. Three Dimensional Live Cell Lithography. Optics Express. 21(8) 10269-10277 (2013).
Farnsworth N., Antunez L., and Bryant S.J. Dynamic Compressive Loading Differentially Regulates Chondrocyte Anabolic and Catabolic Activity with Age. Biotechnology and Bioengineering. 110(7):2046-57 (2013).
2012
Wingate K, Bonani W, Tan Y, Bryant SJ, Tan W. Compressive elasticity of three-dimensional nanofiber matrix directs mesenchymal stem cell differentiation to vascular cells with endothelial or smooth muscle cell markers. Acta Biomaterialia. 8(4):1440-9 (2012).
Hume SL, Hoyt SM, Walker JS, Sridhar BV, Ashley JF, Bowman CN, Bryant SJ. Alignment of multi-layered muscle cells within three-dimensional hydrogel macrochannels. Acta Biomaterialia. 8(6):2193-202 (2012).
Blakney AK, Swartzlander MD, Bryant SJ. The effects of substrate stiffness on the in vitro activation of macrophages and in vivo host response to poly(ethylene glycol)-based hydrogels. Journal of Biomedical Materials Research A. 100(6):1375-86 (2012).
Skaalure SC, Milligan IL, Bryant SJ. Age impacts extracellular matrix metabolism in chondrocytes encapsulated in degradable hydrogels. Biomed Mater. 7(2):024111 (2012).
Farnsworth N., Antunez L., and Bryant S.J. Influence of Chondrocyte Maturation on Acute Response to Impact Injury in PEG Hydrogels. Journal of Biomechanics. 45(15): 2556-2563 (2012).
Farnsworth N., Bensard C., and Bryant S.J. The Role of the PCM in Reducing Oxidative Stress Induced by Radical Initiated Photoencapsulation of Chondrocytes in Poly(ethylene glycol) Hydrogels. Osteoarthritis and Cartilage. 20(11): 1326-1335 (2012).
Steinmetz N.J. and Bryant S.J. Chondroitin sulfate and dynamic loading alter chondrogenesis of human MSCs in PEG hydrogels. Biotechnology and Bioengineering. 109(10): 2671-2682 (2012).
Popp J.R., Roberts J.J., Gallagher D.V., Anseth K.S., Bryant S.J., Quinn T.P. An instrumented bioreactor for mechanical stimulation and real-time, nondestructive evaluation of engineered cartilage tissue. Journal of Medical Devices: 6(2): 021006 (7 pages) (2012).
Vernerey F.J., Greenwald E.C., Bryant S.J. Triphasic mixture model of cell-mediated enzymatic degradation of hydrogels. Computer Methods in Biomechanics and Biomechanical Engineering. 15(11) 1197-1210 (2012).
2011
Steinmetz N.J., Bryant S.J. The Effects of Intermittent Dynamic Loading on Chondrogenic and Osteogenic Differentiation of Human Marrow Stromal Cells Encapsulated in RGD Modified PEG Hydrogels. Acta Biomaterialia. 7: 3829–3840 (2011).
Roberts J.J., Earnshaw A., Ferguson V.R., and Bryant S.J. A comparative study of the viscoelastic mechanical behavior of agarose and poly(ethylene glycol) hydrogels. Journal of Biomedical Materials Research – Part B. 99B: 158–169 (2011).
Roberts J.J., Nicodemus G.D., Giunta S., Bryant S.J. Incorporation of biomimetic matrix molecules into PEG hydrogels enhances matrix deposition and reduces load-induced loss of chondrocyte-secreted matrix. Journal of Biomedical Materials Research Part A. 1;97(3):281-91 (2011).
Roberts J.J., Nicodemus G.D., Greenwald E.C., Bryant S.J. Degradation Improves Tissue Formation in (Un)Loaded Chondrocyte-laden Hydrogels. Clinical Orthopaedics and Related Research. 469(10): 2725-2734 (2011).
Lynn A.D., Blakney A.K., Kyriakides T.R., and Bryant S.J. Temporal progression of the host response to implanted poly(ethyelene glycol)-based hydrogels. Journal of Biomedical Materials Research Part A. 96(4):621-31 (2011).
Nicodemus G.D., Skaalure S.C., and Bryant S.J. Gel structure impacts pericellular and extracellular matrix deposition which subsequently alters metabolic activities in chondrocyte-laden PEG hydrogels. Acta Biomaterialia. 7(2): 492-504 (2011).
Lynn A.D. and Bryant S.J. Phenotypic changes in bone marrow-derived murine macrophages cultured on PEG-based hydrogels activated or not by lipopolysaccharide. Acta Biomaterialia. 7(1): 123–132 (2011).
LaNasa S.M., Hoffecker I., and Bryant S.J .Presence of Pores and Hydrogel Composition Influence Tensile Properties of Scaffolds Fabricated from Well-Defined Sphere Templates. Journal of Biomedical Materials Part B. 96B: 294–302 (2011).
Klouda L., Perkins K.R., Watson B.M., Hacker M.C., Bryant S.J., Raphael R.M., Kasper F.K., Mikos A.G. Thermoresponsive, in situ cross-linkable hydrogels based on N-isopropylacrylamide: fabrication, characterization and mesenchymal stem cell encapsulation. Acta Biomaterialia. 7(4): 1460-1467 (2011).
2010
Villanueva I, Gladem SK, Kessler J, and Bryant SJ. Dynamic loading stimulates chondrocyte biosynthesis when encapsulated in charged hydrogels prepared from poly(ethylene glycol) and chondroitin sulfate. Matrix Biology. 29(1):51-62 (2010).
Screen HRC, Byers SR, Lynn AD, Nguyen V, Patel D, Bryant SJ. Characterization of a Novel Fiber Composite Material for Mechanotransduction Research of Fibrous Connective Tissues. Advanced Functional Materials. 20(5): 738-747 (2010).
Lynn AD, Kyriakides TR, Bryant SJ. Characterization of the in vitro macrophage response and in vivo host response to poly(ethylene glycol)-based hydrogels. Journal of Biomedical Materials Research A. 1;93(3):941-53 (2010).
Jeerage K.M., LaNasa S.M., Hughes H.A., Bryant S.J., Lauria D.S., Slifka A.J. Scanning Electrochemical Measurement of Photopolymerized Poly(ethylene glycol) Hydrogels. Polymer. 51(23): 5456-5461 (2010).
Nicodemus G.D. and Bryant S.J. Mechanical loading regimes affect the anabolic and catabolic activities of chondrocytes encapsulated in PEG hydrogels. Osteoarthritis and Cartilage. 18(1): 126-137 (2010).
2009
Villanueva I, Weigel CA, Bryant SJ. Cell-matrix interactions and dynamic mechanical loading influence chondrocyte gene expression and bioactivity in PEG-RGD hydrogels. Acta Biomaterialia. 5(8):2832-46 (2009).
LaNasa S.M. and Bryant S.J. Influence of ECM proteins and their analogs on skeletal and cardiac muscle cell response when cultured on 2D hydrogels. Acta Biomaterialia. 5: 2929-2938 (2009).
Villanueva I., Bishop N.L., and Bryant S.J. Medium osmolarity and PCM development improves chondrocyte survival when photoencapsulated in PEG hydrogels at low densities. Tissue Engineering Part A. 15(10): 3037-3048 (2009).
Villanueva I., Klement B., von Deutsch D., and Bryant S.J. Crosslinking density alters early metabolic activities in chondrocytes encapsulated in poly(ethylene glycol) hydrogels and cultured in the rotating wall vessel. Biotechnology and Bioengineering. 102(4): 1242-1250 (2009).
Nicodemus G.D., Shiplet K.A., Kaltz S., Bryant S.J. Dynamic compressive loading influences degradation of PEG-PLA hydrogels. Biotechnology and Bioengineering, 102(3):948-59 (2009).
Liang X., Lynn A.D., King D.M., Cavanagh A.S., Bryant S.J., Li P., George S.M., and Weimer A.W. Biocompatible Interface Films Deposited within Porous Polymers by Atomic Layer Deposition. Journal of Applied Materials & Interfaces. 1(9): 1988-1995 (2009).
2008
Bryant SJ, Nicodemus GD, Villanueva I. Designing 3D photopolymer hydrogels to regulate biomechanical cues and tissue growth for cartilage tissue engineering. Pharmaceutical Research. 25(10):2379-86 (2008).
Nicodemus G.D. and Bryant S.J. Cell encapsulation in biodegradable hydrogels for tissue engineering applications. Tissue Engineering Part B: Review, 14(2): 149-165(2008).
Nicodemus G.D. and Bryant S.J. The role of hydrogel structure and dynamic loading on chondrocyte gene expression and matrix formation. Journal of Biomechanics, 41(7): 1528-1536 (2008).
Villanueva I., Hauschulz D.S., Mejic D. and Bryant S.J. Static and dynamic compressive strains influence nitric oxide production and chondrocyte bioactivity when encapsulated in PEG hydrogels of different crosslinking densities. Osteoarthritis and Cartilage, 18(8): 909-918 (2008).
Atzet S., Curtin S., Trinh P., Bryant S., and Ratner B.D. Degradable poly(2-hydroxyethyl methacrylate)-co-polycaprolactone hydrogels for tissue engineering scaffolds. Biomacromolecules, 9(12):3370-3377 (2008).
2007
Nicodemus G.D., Villanueva I. and Bryant S.J. Mechanical Stimulation of TMJ Condylar Chondrocytes encapsulated in PEG Hydrogels. Journal of Biomedical Materials Research, 83A (2):323-331 (2007).
Bryant S.J., Cuy J.L., Hauch K.D. and Ratner B.D. Photo-patterning of porous hydrogels for tissue engineering. Biomaterials, 28: 2978-2986 (2007).
1999-2006
Bryant S.J., Hauch K.D. and Ratner B.D. Spatial Patterning of Thick Poly(2-Hydroxyethyl Methacrylate) Hydrogels. Macromolecules, 39 (13): 4395-4399 (2006).
Bryant S.J., Arthur J.A. and Anseth K.S. Incorporation of tissue-specific molecules alters chondrocyte metabolism and gene expression in photocrosslinked hydrogels. Acta Biomaterialia. 1(2): 243-252 (2005).
Ratner B.D. and Bryant S.J. Biomaterials: Where we’ve been and where we are going. Annual Review of Biomedical Engineering. Vol. 6: 41-75 (2004).
Bryant S.J., Davis-Arehart K.A., Luo N., Shoemaker R.K. and Anseth K.S. Synthesis and characterization of photopolymerized multifunctional hydrogels: water-soluble poly(vinyl alcohol) and chondroitin sulfate macromers for chondrocyte encapsulation. Macromolecules 37(18): 6726-6733 (2004).
Bryant S.J., Anseth K.S., Chowdhury T.T., Lee D.A., and Bader D.L. Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels. Annals of Biomedical Engineering. 32(3):1-12(2004).
Bryant S.J., Anseth K.S., Lee D.A., and Bader D.L. Crosslinking density influences the morphology of chondrocytes photoencapsulated in PEG hydrogels during the application of compressive strain. Journal of Orthopaedic Research. 22(5): 1143-1149 (2004).
Bryant S.J., Bender R.J., Durand K., and Anseth K.S. Encapsulating chondrocytes in degrading PEG hydrogels with high modulus: engineering gel structural changes to facilitate cartilaginous tissue production. Biotechnology and Bioengineering. 86(7): 747-755 (2004).
Bryant S.J., Durand K.L., and Anseth K.S. Manipulations in hydrogel chemistry control photoencapsulated chondrocyte behavior and their extracellular matrix production. Journal of Biomedical Materials Research. 67A: 1430-1436 (2003).
Martens P.J., Bryant S.J., and Anseth K.S. Tailoring the degradation of hydrogels formed from multivinyl poly(ethylene glycol) and poly(vinyl alcohol) macromers for cartilage tissue engineering. Biomacromolecules. 4(2): 283-292 (2003).
Bryant S.J. and Anseth K.S. Controlling the spatial distribution of ECM components in degradable PEG hydrogels for tissue engineering cartilage. Journal of Biomedical Materials Research. 64A(1):70-79(2003).
Anseth K.S., Metters A.T., Bryant S.J., Martens P.J., Elisseeff J.H., Bowman C.N. In situ forming degradable networks and their application in tissue engineering and drug delivery. Journal of Controlled Release. 78:199-209 (2001).
Bryant S.J. and Anseth K.S. Hydrogel properties influence ECM production by chondrocytes photoencapsulated in poly(ethylene glycol) hydrogels. Journal of Biomedical Materials Research. 59: 63-72 (2002).
Bryant S.J. and Anseth K.S. The effects of scaffold thickness on tissue engineered cartilage in photocrosslinked poly(ethylene oxide) hydrogels. Biomaterials. 22: 619-626 (2001).
Bryant S.J., Nuttelman C.R. and Anseth K.S. Cytocompatibility of Ultraviolet and Visible Light Photoinitiating Systems on Cultured NIH/3T3 Fibroblasts In Vitro. Journal of Biomaterials Science. Polymer Edition. 11(5): 439-457 (2000).
Bryant S.J., Nuttelman C.R. and Anseth K.S. The effects of crosslinking density on cartilage formation in photocrosslinkable hydrogels. Biomedical Science Instrumentation. 35: 309-314 (1999).
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