aaron whiteley
Assistant Professor

Office: JSCBB B221
Lab: JSCBB B255
Lab Phone: 303-735-3901

Education

PhD: Infectious Diseases and Immunity; Advisor: Dr. Daniel Portnoy. University of California Berkeley, 2010-2016
Postdoctoral Fellow: Microbiology; Advisors: Dr. John Mekalanos and Dr. Philip Kranzusch. Harvard Medical School, 2016-2019

Areas of Expertise

Bacteriology, Pathogenesis, Innate Immunity, Nucleic Acids & Gene Expression, Cell Signaling, and Proteins & Enzymology.

For a full list, please see: https://www.ncbi.nlm.nih.gov/myncbi/aaron.whiteley.1/bibliography/public/

  • Whiteley, A.T., Eaglesham, J.B., de Oliveira Mann, C.C., Morehouse, B.R., Lowey, B., Nieminen, E.A., Danilchanka, O., King, D.S., Lee, A.S.Y, Mekalanos, J.J.*, Kranzusch, P.J.* Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature (2019). (*co-cor. author). PMC6544370
  • Zhou, W.*, Whiteley, A. T.*, de Oliveira Mann, C.C., Morehouse, B.R., Nowak, R.P., Fischer, E.S., Gray, N.S., Mekalanos, J.J., Kranzusch, P.J. Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance. Cell (2018). (*equal contributions). PMC6084792
  • Whiteley, A.T., Garelis, N.E., Peterson, B.N., Choi, PH., Tong, L., Woodward, J.J., Portnoy, D.A. c- di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance, and osmoregulation. Mol. Microbiology (2017). PMC5391996
  • Reniere, M.L.*, Whiteley, A.T.*, and Portnoy, D.A. An in vivo selection identifies Listeria monocytogenes genes required to sense the intracellular environment and activate virulence factor expression. PLoS Pathogens (2016). (*equal contributions). PMC4945081
  • Whiteley, A.T., Pollock, A.J., and Portnoy, D.A. The PAMP c-di-AMP Is Essential for Listeria monocytogenes Growth in Rich but Not Minimal Media due to a Toxic Increase in (p)ppGpp. Cell Host & Microbe (2015). PMC4469362