Department of Integrative Physiology
Ramaley N379A
University of Colorado
Boulder, CO 80309-0354
Christopher A. Lowry, Ph.D., is an Associate Professor in the Department of Integrative Physiology and Center for Neuroscience at the University of Colorado Boulder, with a secondary appointment in the Department of Physical Medicine and Rehabilitation (PM&R) and Center for Neuroscience at the University of Colorado Anschutz Medical Campus (AMC), a Principal Investigator in the Department of Veterans Affairs Eastern Colorado Health Care System, VA Rocky Mountain Mental Illness Research, Education, & Clinical Center (MIRECC), Denver Veterans Affairs Medical Center (VAMC), and director of the Behavioral Neuroendocrinology Laboratory at CU Boulder. He is Co-Director, with Dr. Lisa Brenner, of the Military and Veteran Microbiome Consortium for Research and Education (MVM-CoRE). Dr. Lowry's research program focuses on understanding stress-related physiology and behavior with an emphasis on the role of the microbiome-gut-brain axis in stress resilience, health and disease.
Selected Publications:
Lowry CA, Hollis JH, de Vries A, Pan B, Rosa Brunet L, Hunt JRF, Paton JFR, van Kampen E, Knight DM, Evans AK, Rook GAW, Lightman SL. Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior. Neuroscience 146: 756-772, 2007.
Gardner KL, Hale MW, Oldfield S, Lightman SL, Plotsky PM, Lowry CA. Adverse experience during early life and adulthood interact to elevate tph2 expression in serotonergic neurons within the dorsal raphe nucleus. Neuroscience 163: 991-1001, 2009.
Raison CL, Lowry CA, Rook GA. Inflammation, sanitation, and consternation: loss of contact with coevolved, tolerogenic microorganisms and the pathophysiology and treatment of major depression. Arch Gen Psychiatry 67: 1211-1224, 2010.
Hale MW, Dady KF, Evans AK, Lowry CA. Evidence for In vivo thermosensitivity of serotonergic neurons in the rat dorsal raphe nucleus and raphe pallidus nucleus implicated in thermoregulatory cooling. Exp Neurol 227:264-278, 2011.
Hale MW and Lowry, CA. Functional topography of midbrain and pontine serotonergic systems: implications for synaptic regulation of serotonergic circuits. Psychopharmacology (Berl) 213: 243-264, 2011.