Rates

HTS Application Form

Academic Users:

a. HTS service includes assistance on assay optimization and automation, screening of the Maybridge Hitfinder library of 14, 400 compounds in replicate, and cherry-picking no more than 145 compounds (1% of the library) per screen for further validation;
b.  PS service includes providing 1,000 compounds (i.e., 3 384-well compound plates) for each screen, and cherry-picking no more than 10 compounds (1% of the screen collection) per screen for further validation.

Effective Date: July 1, 2015

Notes on Authorship

Co-authorship is generally expected when core personnel have made significant contributions to the research in the form of consultation, experimental design, method development, data analysis and/or data interpretation. Significant is defined as “the project would not have progressed, or progressed at a substantially slower pace, without the guidance of facility personnel”. In such cases, core personnel should have the opportunity to review and edit the appropriate sections of a manuscript before submission.

Acknowledgement of facility contributions is expected in publications that include any data generated in the facility or using core instrumentation or software. An example of an appropriate acknowledgement is “The authors wish to thank the High Throughput and High Content Screening Core at the University of Colorado at Boulder for their contributions to this manuscript”.

Please inform us when relevant publications are accepted, as we would like to post citations on our website. This information is vital to the continued support of the facility.

Grant Assistance and Percent Effort

We are very happy to provide letters of support and assistance in grant writing. For letters of support, please allow at least 2 weeks from the time of your request. Please furnish the following information: Title of grant, agency to which you are submitting the grant, your title and mailing address, and 1-3 sentences on the goals (or specific aims) of your proposal.

Our facility is also dependent on grant support for long-term success and we appreciate your support in keeping the facility funded. To determine if percent effort by core personnel is required, please consider the following:

• Does the proposal include a specific aim(s) that focuses on high throughput screening and/or high content analysis?
• Is method development required?
• Is data analysis development required (often the case with high content work)?
• Would the aim or proposal not receive a favorable review without the support of Core personnel?
• Would the project not have progressed, or progressed at a substantially slower pace, without the guidance of facility personnel?