Our research bridges computational and experimental sciences to discover new regulatory aspects in the human genome - - Specifically how long noncoding RNA (lncRNA) genes regulate numerous biological processes. We have continually applied and developed many technologies such as single-molecule RNA imaging, RNA-sequencing, Single Cell RNA-sequencing, CRISPR-Display and SNP-CLING. This multifaceted and cross-disciplinary approach is focused on unraveling the molecular modalities underlying RNA biology and in turn how it regulates cell state.
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Our teaching of University of Colorado Biochemistry Undergraduate and Graduate Students aims to enable all students to perform bioinformatic and data science analyses on ever emerging forms of genome-wide data such as RNA-seq, ChIP-seq, ATAC-seq.
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