Office: JSCBB B320
Lab: JSCBB B350
Lab Phone: 303-492-2508
Ph.D.: University of Colorado Boulder, 2001
Areas of Expertise
Cell Signaling, Molecular Biophysics, Nucleic Acids, Proteins & Enzymology
Mammalian mRNA Transcription and its Regulation
The underlying goal of our research is to uncover molecular mechanisms governing mammalian mRNA transcription which is carried out by the enzyme RNA polymerase II. To this end, we use a combination of biochemistry, molecular biology, cell-based techniques, molecular genetics, and single molecule studies to investigate mechanisms of transcription and its regulation in multiple biochemical and cellular systems.