3D resolution capabilities of two optical microscope systems. Ont he left is a confocal microscope 3D image that appears stretched in the vertical (axial) direction. On the right is a new 3D super-resolution method that correctly resolves all three dimensions. We study and develop optical microscopes that help biologists and engineers address their questions more quantitatively and accurately, and we do so by extending the capability of optical imaging beyond traditional limitations.​

Our research interests include extending the depth of field of imaging systems, increasing image resolution beyond Rayleigh's resolution criterion, and quantifying the optical path length distributions of transparent objects. To explore these topics, we utilize a wide range of innovative techniques such as point spread function engineering, differential interferometry, multiplexed optical scanning, computational imaging, and numerical optimization.