Relevant Publications
- Nandakumar, J., Bell, C.F., Weidenfeld, I., Zaug, A.J., Leinwand, L.A., Cech, T.R. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature 492: 285-289 (2012).
- Borah, S., Xi, L., Zaug, A.J., Powell, N.M., Dancik, G.M., Cohen, S.B., Costello, J.C., Theodorescu, D., & Cech, T.R. TERT promoter mutations and telomerase reactivation in urothelial cancer. Science 347: 1006-1010 (2015).
- Stern, JL, Theodorescu, D, Vogelstein, B, Papadopoulos, N, Cech, TR. Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers. Genes Dev. 29: 2219-2224. (2015).
- Schmidt, J. C., Zaug, A. J. and Cech, T. R. Live cell imaging reveals dynamic interactions that drive telomerase recruitment to telomeres. Cell 166: 1188-1197 (2016).
- Wang, X., Paucek, R.D., Gooding, A.R., Brown, Z.Z., Ge, E.J., Muir, T.W., & Cech, T.R. Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA. Nat. Struc. Mol. Biol. 24: 1028-1038 (2017).
- Youmans, D. T., Schmidt, J. C., & Cech, T. R. Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunits. Genes Dev, 32: 794-805. (2018).
