Global Proteomics Via Mass Spectrometry

Global proteomics is the method by which the entire proteome of a sample (tissues, cells, or even subcellular fractions) is identified and quantified. This highly technical method is used by our laboratory to determine the global effects of proteome disruption in cancer and neurodegenerative disease, which provides a huge advantage when studying UBQLN biology. Proteomics is performed by the Mass Spectrometry Facility at the JSCBB.