(updated July 2022)

Graphical Abstract

Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance

July 12, 2018

Zhou W*, ➤Whiteley AT*, de Oliveira Mann CC, Morehouse BR, Nowak RP, Fischer ES, Gray NS, Mekalanos JJ, Kranzusch PJ. | Cell. 2018

Mitchell et al 2017 Summary

Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy

Dec. 26, 2017

Mitchell G, Cheng MI, Chen C, Nguyen BN, ➤Whiteley AT, Kianian S, Cox JS, Green DR, McDonald KL, Portnoy DA. | PNAS. 2018

Activation of the Listeria monocytogenes Virulence Program by a Reducing Environment

Oct. 17, 2017

Portman JL, Dubensky SB, Peterson BN, ➤Whiteley AT, Portnoy DA. | mBio. 2017

A Redox-Responsive Transcription Factor Is Critical for Pathogenesis and Aerobic Growth of Listeria monocytogenes

April 21, 2017

➤Whiteley AT, Ruhland BR, Edrozo MB, Reniere ML. | Infect Immun. 2017

c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation

April 1, 2017

➤Whiteley AT, Garelis NE, Peterson BN, Choi PH, Tong L, Woodward JJ, Portnoy DA. | Mol Microbiol. 2017

An In Vivo Selection Identifies Listeria monocytogenes Genes Required to Sense the Intracellular Environment and Activate Virulence Factor Expression

July 14, 2016

Reniere ML*, ➤Whiteley AT*, Portnoy DA. | PLoS Pathog. 2016

The PAMP c-di-AMP Is Essential for Listeria monocytogenes Growth in Rich but Not Minimal Media due to a Toxic Increase in (p)ppGpp

June 10, 2015

Whiteley AT, Pollock AJ, Portnoy DA. | Cell Host Microbe. 2015

RNA-Based Fluorescent Biosensors for Live Cell Imaging of Second Messenger Cyclic di-AMP

May 15, 2015

Kellenberger CA, Chen C, Whiteley AT, Portnoy DA, Hammond MC. | J Am Chem Soc. 2015

Glutathione activates virulence gene expression of an intracellular pathogen

Jan. 8, 2015

Reniere ML, Whiteley AT, Hamilton KL, John SM, Lauer P, Brennan RG, Portnoy DA. | Nature. 2015

Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection

May 28, 2013

Witte CE, Whiteley AT, Burke TP, Sauer JD, Portnoy DA, Woodward JJ. | mBio. 2013