(updated October 2020)

JB Commentary

The linguistics of bacterial conflict systems reveal ancient origins of eukaryotic innate immunity

Nov. 19, 2020

Kibby EM, ➤Whiteley AT. | J. Bacteriology 2020

Model Figure

Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling

Nov. 3, 2020

Chang D, ➤Whiteley AT, Bugda Gwilt K, Lencer WI, Mekalanos JJ*, Thiagarajah JR* | PNAS 2020

Model Figure

(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes.

Aug. 25, 2020

Peterson BN, Young MKM, Luo S, Wang J, ➤Whiteley AT, Woodward JJ, Tong L, Wang JD, Portnoy DA. | mBio. 2020

Graphical Abstract

CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection

July 9, 2020

Lowey B, ➤Whiteley AT, Keszei AFA, Morehouse BR, Mathews IT, Antine SP, Cabrera VJ, Kashin D, Niemann P, Jain M, Schwede F, Mekalanos JJ, Shao S, Lee ASY, Kranzusch PJ. | Cell. 2020

Graphical Abstract

Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity

Jan. 6, 2020

Lau RK, Ye Q, Birkholz EA, Berg KR, Patel L, Mathews IT, Watrous JD, Ego K, ➤Whiteley AT, Lowey B, Mekalanos JJ, Kranzusch PJ, Jain M, Pogliano J, Corbett KD. | Mol Cell. 2020

Fig 1 of Methods Paper

Analysis of human cGAS activity and structure

May 2, 2019

Zhou W, ➤Whiteley AT, Kranzusch PJ. | Methods Enzymol. 2019

CD-NTase Tree

Bacterial cGAS-like enzymes synthesize diverse nucleotide signals

March 1, 2019

➤Whiteley AT, Eaglesham JB, de Oliveira Mann CC, Morehouse BR, Lowey B, Nieminen EA, Danilchanka O, King DS, Lee ASY, Mekalanos JJ*, Kranzusch PJ* | Nature. 2019

Graphical Abstract

Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance

July 12, 2018

Zhou W*, ➤Whiteley AT*, de Oliveira Mann CC, Morehouse BR, Nowak RP, Fischer ES, Gray NS, Mekalanos JJ, Kranzusch PJ. | Cell. 2018

Mitchell et al 2017 Summary

Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy

Dec. 26, 2017

Mitchell G, Cheng MI, Chen C, Nguyen BN, ➤Whiteley AT, Kianian S, Cox JS, Green DR, McDonald KL, Portnoy DA. | PNAS. 2018

Activation of the Listeria monocytogenes Virulence Program by a Reducing Environment

Oct. 17, 2017

Portman JL, Dubensky SB, Peterson BN, ➤Whiteley AT, Portnoy DA. | mBio. 2017