Selected Publications

  • Pawlikowski B, Vogler TO, Gadek K, Olwin BB. Regulation of skeletal muscle stem cells by fibroblast growth factors. Dev Dyn. 2017 May;246(5):359-367. PubMed PMID: 28249356.
  • Hall MN, Hall JK, Cadwallader AB, Pawlikowski BT, Doles JD, et al. Transplantation of Skeletal Muscle Stem Cells. Methods Mol Biol. 2017;1556:237-244. PubMed PMID: 28247353.
  • Chenette DM, Cadwallader AB, Antwine TL, Larkin LC, Wang J, et al. Targeted mRNA Decay by RNA Binding Protein AUF1 Regulates Adult Muscle Stem Cell Fate, Promoting Skeletal Muscle Integrity. Cell Rep. 2016 Aug 2;16(5):1379-90. PubMed PMID: 27452471; NIHMSID: NIHMS804944; PubMed Central PMCID: PMC5323095.
  • Harper SC, Brack A, MacDonnell S, Franti M, Olwin BB, et al. Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects?. Circ Res. 2016 Apr 1;118(7):1143-50; discussion 1150. PubMed PMID: 27034276; NIHMSID: NIHMS766728; PubMed Central PMCID: PMC4829942.
  • Vogler TO, Gadek KE, Cadwallader AB, Elston TL, Olwin BB. Isolation, Culture, Functional Assays, and Immunofluorescence of Myofiber-Associated Satellite Cells. Methods Mol Biol. 2016;1460:141-62. PubMed PMID: 27492171.
  • Pisconti A, Banks GB, Babaeijandaghi F, Betta ND, Rossi FM, et al. Loss of niche-satellite cell interactions in syndecan-3 null mice alters muscle progenitor cell homeostasis improving muscle regeneration. Skelet Muscle. 2016;6:34. PubMed PMID: 27757223; PubMed Central PMCID: PMC5064903.
  • Bustos F, de la Vega E, Cabezas F, Thompson J, Cornelison DD, et al. NEDD4 Regulates PAX7 Levels Promoting Activation of the Differentiation Program in Skeletal Muscle Precursors. Stem Cells. 2015 Oct;33(10):3138-51. PubMed PMID: 26304770; NIHMSID: NIHMS712893; PubMed Central PMCID: PMC4579044.
  • Doles JD, Olwin BB. Muscle stem cells on the edge. Curr Opin Genet Dev. 2015 Oct;34:24-8. PubMed PMID: 26189082.
  • Hausburg MA, Doles JD, Clement SL, Cadwallader AB, Hall MN, et al. Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay. Elife. 2015 Mar 27;4:e03390. PubMed PMID: 25815583; PubMed Central PMCID: PMC4415119.
  • Pawlikowski B, Pulliam C, Betta ND, Kardon G, Olwin BB. Pervasive satellite cell contribution to uninjured adult muscle fibers. Skelet Muscle. 2015;5:42. PubMed PMID: 26668715; PubMed Central PMCID: PMC4677447.
  • Doles JD, Olwin BB. The impact of JAK-STAT signaling on muscle regeneration. Nat Med. 2014 Oct;20(10):1094-5. PubMed PMID: 25295935; NIHMSID: NIHMS683607; PubMed Central PMCID: PMC4426494.
  • Bernet JD, Doles JD, Hall JK, Kelly Tanaka K, Carter TA, et al. p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice. Nat Med. 2014 Mar;20(3):265-71. PubMed PMID: 24531379; NIHMSID: NIHMS555421; PubMed Central PMCID: PMC4070883.
  • Farina NH, Hausburg M, Betta ND, Pulliam C, Srivastava D, et al. A role for RNA post-transcriptional regulation in satellite cell activation. Skelet Muscle. 2012 Oct 9;2(1):21. PubMed PMID: 23046558; PubMed Central PMCID: PMC3563611.
  • Troy A, Cadwallader AB, Fedorov Y, Tyner K, Tanaka KK, et al. Coordination of satellite cell activation and self-renewal by Par-complex-dependent asymmetric activation of p38α/β MAPK. Cell Stem Cell. 2012 Oct 5;11(4):541-53. PubMed PMID: 23040480; NIHMSID: NIHMS584991; PubMed Central PMCID: PMC4077199.
  • Parker MH, Loretz C, Tyler AE, Duddy WJ, Hall JK, et al. Activation of Notch signaling during ex vivo expansion maintains donor muscle cell engraftment. Stem Cells. 2012 Oct;30(10):2212-20. PubMed PMID: 22865615; NIHMSID: NIHMS398922; PubMed Central PMCID: PMC3448880.
  • Pisconti A, Bernet JD, Olwin BB. Syndecans in skeletal muscle development, regeneration and homeostasis. Muscles Ligaments Tendons J. 2012 Jan;2(1):1-9. PubMed PMID: 23738267; PubMed Central PMCID: PMC3666495.
  • Doyle MJ, Zhou S, Tanaka KK, Pisconti A, Farina NH, et al. Abcg2 labels multiple cell types in skeletal muscle and participates in muscle regeneration. J Cell Biol. 2011 Oct 3;195(1):147-63. PubMed PMID: 21949413; PubMed Central PMCID: PMC3187700.
  • Bren-Mattison Y, Hausburg M, Olwin BB. Growth of limb muscle is dependent on skeletal-derived Indian hedgehog. Dev Biol. 2011 Aug 15;356(2):486-95. PubMed PMID: 21683695; NIHMSID: NIHMS304478; PubMed Central PMCID: PMC3322465.
  • Olguín HC, Patzlaff NE, Olwin BB. Pax7-FKHR transcriptional activity is enhanced by transcriptionally repressed MyoD. J Cell Biochem. 2011 May;112(5):1410-7. PubMed PMID: 21321994; NIHMSID: NIHMS274359; PubMed Central PMCID: PMC3071457.
  • Hall JK, Banks GB, Chamberlain JS, Olwin BB. Prevention of muscle aging by myofiber-associated satellite cell transplantation. Sci Transl Med. 2010 Nov 10;2(57):57ra83. PubMed PMID: 21068442; NIHMSID: NIHMS474113; PubMed Central PMCID: PMC4438676.
  • Pisconti A, Cornelison DD, Olguín HC, Antwine TL, Olwin BB. Syndecan-3 and Notch cooperate in regulating adult myogenesis. J Cell Biol. 2010 Aug 9;190(3):427-41. PubMed PMID: 20696709; PubMed Central PMCID: PMC2922652.
  • Shi H, Boadu E, Mercan F, Le AM, Flach RJ, et al. MAP kinase phosphatase-1 deficiency impairs skeletal muscle regeneration and exacerbates muscular dystrophy. FASEB J. 2010 Aug;24(8):2985-97. PubMed PMID: 20371627; PubMed Central PMCID: PMC2909286.
  • Tanaka KK, Hall JK, Troy AA, Cornelison DD, Majka SM, et al. Syndecan-4-expressing muscle progenitor cells in the SP engraft as satellite cells during muscle regeneration. Cell Stem Cell. 2009 Mar 6;4(3):217-25. PubMed PMID: 19265661; NIHMSID: NIHMS99791; PubMed Central PMCID: PMC3142572.
  • Olguin HC, Yang Z, Tapscott SJ, Olwin BB. Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination. J Cell Biol. 2007 Jun 4;177(5):769-79. PubMed PMID: 17548510; PubMed Central PMCID: PMC2064278.
  • Jones NC, Tyner KJ, Nibarger L, Stanley HM, Cornelison DD, et al. The p38alpha/beta MAPK functions as a molecular switch to activate the quiescent satellite cell. J Cell Biol. 2005 Apr 11;169(1):105-16. PubMed PMID: 15824134; PubMed Central PMCID: PMC2171902.
  • Olguin HC, Olwin BB. Pax-7 up-regulation inhibits myogenesis and cell cycle progression in satellite cells: a potential mechanism for self-renewal. Dev Biol. 2004 Nov 15;275(2):375-88. PubMed PMID: 15501225; NIHMSID: NIHMS2214; PubMed Central PMCID: PMC3322464.
  • Cornelison DD, Wilcox-Adelman SA, Goetinck PF, Rauvala H, Rapraeger AC, et al. Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration. Genes Dev. 2004 Sep 15;18(18):2231-6. PubMed PMID: 15371336; PubMed Central PMCID: PMC517515.
  • Bren-Mattison Y, Olwin BB. Sonic hedgehog inhibits the terminal differentiation of limb myoblasts committed to the slow muscle lineage. Dev Biol. 2002 Feb 15;242(2):130-48. PubMed PMID: 11820811.
  • Fedorov YV, Jones NC, Olwin BB. Atypical protein kinase Cs are the Ras effectors that mediate repression of myogenic satellite cell differentiation. Mol Cell Biol. 2002 Feb;22(4):1140-9. PubMed PMID: 11809805; PubMed Central PMCID: PMC134628.
  • Cornelison DD, Filla MS, Stanley HM, Rapraeger AC, Olwin BB. Syndecan-3 and syndecan-4 specifically mark skeletal muscle satellite cells and are implicated in satellite cell maintenance and muscle regeneration. Dev Biol. 2001 Nov 1;239(1):79-94. PubMed PMID: 11784020.
  • Fedorov YV, Rosenthal RS, Olwin BB. Oncogenic Ras-induced proliferation requires autocrine fibroblast growth factor 2 signaling in skeletal muscle cells. J Cell Biol. 2001 Mar 19;152(6):1301-5. PubMed PMID: 11257129; PubMed Central PMCID: PMC2199216.
  • Jones NC, Fedorov YV, Rosenthal RS, Olwin BB. ERK1/2 is required for myoblast proliferation but is dispensable for muscle gene expression and cell fusion. J Cell Physiol. 2001 Jan;186(1):104-15. PubMed PMID: 11147804.
  • Cornelison DD, Olwin BB, Rudnicki MA, Wold BJ. MyoD(-/-) satellite cells in single-fiber culture are differentiation defective and MRF4 deficient. Dev Biol. 2000 Aug 15;224(2):122-37. PubMed PMID: 10926754.
  • Köhl R, Antoine M, Olwin BB, Dickson C, Kiefer P. Cysteine-rich fibroblast growth factor receptor alters secretion and intracellular routing of fibroblast growth factor 3. J Biol Chem. 2000 May 26;275(21):15741-8. PubMed PMID: 10748074.
  • Flanagan-Steet H, Hannon K, McAvoy MJ, Hullinger R, Olwin BB. Loss of FGF receptor 1 signaling reduces skeletal muscle mass and disrupts myofiber organization in the developing limb. Dev Biol. 2000 Feb 1;218(1):21-37. PubMed PMID: 10644408.
  • Fedorov YV, Jones NC, Olwin BB. Regulation of myogenesis by fibroblast growth factors requires beta-gamma subunits of pertussis toxin-sensitive G proteins. Mol Cell Biol. 1998 Oct;18(10):5780-7. PubMed PMID: 9742095; PubMed Central PMCID: PMC109164.
  • Jhaveri S, Olwin B, Ellington AD. In vitro selection of phosphorothiolated aptamers. Bioorg Med Chem Lett. 1998 Sep 8;8(17):2285-90. PubMed PMID: 9873529.
  • Kudla AJ, Jones NC, Rosenthal RS, Arthur K, Clase KL, et al. The FGF receptor-1 tyrosine kinase domain regulates myogenesis but is not sufficient to stimulate proliferation. J Cell Biol. 1998 Jul 13;142(1):241-50. PubMed PMID: 9660877; PubMed Central PMCID: PMC2133035.
  • Zuber ME, Zhou Z, Burrus LW, Olwin BB. Cysteine-rich FGF receptor regulates intracellular FGF-1 and FGF-2 levels. J Cell Physiol. 1997 Mar;170(3):217-27. PubMed PMID: 9066777.
  • Zhou Z, Zuber ME, Burrus LW, Olwin BB. Identification and characterization of a fibroblast growth factor (FGF) binding domain in the cysteine-rich FGF receptor. J Biol Chem. 1997 Feb 21;272(8):5167-74. PubMed PMID: 9030584.
  • Hannon K, Kudla AJ, McAvoy MJ, Clase KL, Olwin BB. Differentially expressed fibroblast growth factors regulate skeletal muscle development through autocrine and paracrine mechanisms. J Cell Biol. 1996 Mar;132(6):1151-9. PubMed PMID: 8601591; PubMed Central PMCID: PMC2120753.
  • Patrie KM, Kudla AJ, Olwin BB, Chiu IM. Conservation of ligand specificity between the mammalian and amphibian fibroblast growth factor receptors. J Biol Chem. 1995 Dec 1;270(48):29018-24. PubMed PMID: 7499435.
  • Szebenyi G, Savage MP, Olwin BB, Fallon JF. Changes in the expression of fibroblast growth factor receptors mark distinct stages of chondrogenesis in vitro and during chick limb skeletal patterning. Dev Dyn. 1995 Dec;204(4):446-56. PubMed PMID: 8601037.
  • Kudla AJ, John ML, Bowen-Pope DF, Rainish B, Olwin BB. A requirement for fibroblast growth factor in regulation of skeletal muscle growth and differentiation cannot be replaced by activation of platelet-derived growth factor signaling pathways. Mol Cell Biol. 1995 Jun;15(6):3238-46. PubMed PMID: 7760819; PubMed Central PMCID: PMC230556.
  • DeHamer MK, Guevara JL, Hannon K, Olwin BB, Calof AL. Genesis of olfactory receptor neurons in vitro: regulation of progenitor cell divisions by fibroblast growth factors. Neuron. 1994 Nov;13(5):1083-97. PubMed PMID: 7946347.
  • Olwin BB, Arthur K, Hannon K, Hein P, McFall A, et al. Role of FGFs in skeletal muscle and limb development. Mol Reprod Dev. 1994 Sep;39(1):90-100; discussion 100-1. PubMed PMID: 7999366. 
  • Fallon JF, López A, Ros MA, Savage MP, Olwin BB, et al. FGF-2: apical ectodermal ridge growth signal for chick limb development. Science. 1994 Apr 1;264(5155):104-7. PubMed PMID: 7908145.
  • Rapraeger AC, Guimond S, Krufka A, Olwin BB. Regulation by heparan sulfate in fibroblast growth factor signaling. Methods Enzymol. 1994;245:219-40. PubMed PMID: 7760735.
  • Olwin BB, Hannon K, Kudla AJ. Are fibroblast growth factors regulators of myogenesis in vivo?. Prog Growth Factor Res. 1994;5(2):145-58. PubMed PMID: 7919221.
  • Guimond S, Maccarana M, Olwin BB, Lindahl U, Rapraeger AC. Activating and inhibitory heparin sequences for FGF-2 (basic FGF) Distinct requirements for FGF-1, FGF-2, and FGF-4. J Biol Chem. 1993 Nov 15;268(32):23906-14. PubMed PMID: 7693696. 
  • Savage MP, Hart CE, Riley BB, Sasse J, Olwin BB, et al. Distribution of FGF-2 suggests it has a role in chick limb bud growth. Dev Dyn. 1993 Nov;198(3):159-70. PubMed PMID: 8136521. 
  • Riley BB, Savage MP, Simandl BK, Olwin BB, Fallon JF. Retroviral expression of FGF-2 (bFGF) affects patterning in chick limb bud. Development. 1993 May;118(1):95-104. PubMed PMID: 8375342.
  • Olwin BB, Riley B, Fallon JF. A method for ectopic expression of foreign genes in the chicken limb in vivo. Prog Clin Biol Res. 1993;383B:635-43. PubMed PMID: 8115379.
  • Riley DA, Bain JL, Olwin BB. Immunolocalization of a cysteine-rich FGF receptor in chicken embryos. Prog Clin Biol Res. 1993;383B:655-65. PubMed PMID: 8115381.
  • Burrus LW, Zuber ME, Lueddecke BA, Olwin BB. Identification of a cysteine-rich receptor for fibroblast growth factors. Mol Cell Biol. 1992 Dec;12(12):5600-9. PubMed PMID: 1448090; PubMed Central PMCID: PMC360499.
  • Casscells W, Lappi DA, Olwin BB, Wai C, Siegman M, et al. Elimination of smooth muscle cells in experimental restenosis: targeting of fibroblast growth factor receptors. Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):7159-63. PubMed PMID: 1323129; PubMed Central PMCID: PMC49665.
  • Olwin BB, Rapraeger A. Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate. J Cell Biol. 1992 Aug;118(3):631-9. PubMed PMID: 1379245; PubMed Central PMCID: PMC2289538. 
  • Rapraeger AC, Krufka A, Olwin BB. Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation. Science. 1991 Jun 21;252(5013):1705-8. PubMed PMID: 1646484
  • Doctor JS, Hoffmann FM, Olwin BB. Identification of a fibroblast growth factor-binding protein in Drosophila melanogaster. Mol Cell Biol. 1991 Apr;11(4):2319-23. PubMed PMID: 1848676; PubMed Central PMCID: PMC359941. 
  • Olwin BB, Burrus LW, Zuber ME, Lueddecke B. Characterization of a non-tyrosine kinase FGF-binding protein. Ann N Y Acad Sci. 1991;638:195-203. PubMed PMID: 1723853
  • Olwin BB, Hauschka SD. Fibroblast growth factor receptor levels decrease during chick embryogenesis. J Cell Biol. 1990 Feb;110(2):503-9. PubMed PMID: 2153684; PubMed Central PMCID: PMC2115997. 
  • Olwin BB. Heparin-binding growth factors and their receptors. Cytotechnology. 1989 Dec;2(4):351-65. PubMed PMID: 22358874.
  • Burrus LW, Olwin BB. Isolation of a receptor for acidic and basic fibroblast growth factor from embryonic chick. J Biol Chem. 1989 Nov 5;264(31):18647-53. PubMed PMID: 2553717.
  • Olwin BB, Hauschka SD. Cell type and tissue distribution of the fibroblast growth factor receptor. J Cell Biochem. 1989 Apr;39(4):443-54. PubMed PMID: 2542345.
  • Olwin BB, Hauschka SD. Cell surface fibroblast growth factor and epidermal growth factor receptors are permanently lost during skeletal muscle terminal differentiation in culture. J Cell Biol. 1988 Aug;107(2):761-9. PubMed PMID: 2843547; PubMed Central PMCID: PMC2115215. 
  • Seed J, Olwin BB, Hauschka SD. Fibroblast growth factor levels in the whole embryo and limb bud during chick development. Dev Biol. 1988 Jul;128(1):50-7. PubMed PMID: 2838349. 
  • Clegg CH, Linkhart TA, Olwin BB, Hauschka SD. Growth factor control of skeletal muscle differentiation: commitment to terminal differentiation occurs in G1 phase and is repressed by fibroblast growth factor. J Cell Biol. 1987 Aug;105(2):949-56. PubMed PMID: 3624313; PubMed Central PMCID: PMC2114757.
  • Pelech SL, Olwin BB, Krebs EG. Fibroblast growth factor treatment of Swiss 3T3 cells activates a subunit S6 kinase that phosphorylates a synthetic peptide substrate. Proc Natl Acad Sci U S A. 1986 Aug;83(16):5968-72. PubMed PMID: 3461469; PubMed Central PMCID: PMC386418. 
  • Olwin BB, Hauschka SD. Identification of the fibroblast growth factor receptor of Swiss 3T3 cells and mouse skeletal muscle myoblasts. Biochemistry. 1986 Jun 17;25(12):3487-92. PubMed PMID: 3013291. 
  • Olwin BB, Hall ZW. Developmental regulation of laminin accumulation in the extracellular matrix of a mouse muscle cell line. Dev Biol. 1985 Dec;112(2):359-67. PubMed PMID: 3908195.
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