betterton
We collaborated with the Detweiler lab to apply image quantification tools to their study of novel potential antibiotic compounds.
Recent work has shown that the C-terminal tail is particularly important to kinesin-5 motor function and mitotic spindle assembly. We characterized a series of kinesin-5/Cut7 tail truncation alleles in fission yeast. Our observations suggest that the C-terminal tail of Cut7p contributes to both sliding force and midzone localization.
We describe the Toolkit for Automated Microtubule Tracking (TAMiT), which automatically detects, optimizes, and tracks fluorescent microtubules in living yeast cells with sub-pixel accuracy. TAMiT detects linear and curved polymers using a geometrical scanning technique.
Congratulations to Saad Ansari for successfully defending his PhD thesis today.
We show evidence for micron-scale communication between nanometer-sized motors.
Toward task capable active matter: learning to avoid clogging in confined collectives via collisionsA robotic excavating swarm with simple learning rules can mitigate jams.
Congratulations to Shane Fiorenza for successfully defending his PhD thesis today.
We describe a new simulation framework for motor protein and crosslinker interaction with microtubules in a lattice model.
Our paper "CyLaKS: the Cytoskeleton Lattice-based Kinetic Simulator" was posted to bioRxiv today.
Our paper "Comparison of explicit and mean-field models of cytoskeletal filaments with crosslinking motors" was published in European Physical Journal E today.