Welcome to the Ahn Lab at the University of Colorado Boulder!

The Ahn lab explores molecular mechanisms controlling the dynamics of cell signaling in mammalian systems. Our research examines internal motions in protein kinases and their impact on kinase activation and small molecule inhibition, the control of cell polarity and migration by membrane trafficking, and mechanisms for therapy resistance in cancer cells.  To this end, our research includes proteomics methods for profiling proteins and post-translational modifications by mass spectrometry, analysis of protein allostery by hydrogen-deuterium exchange mass spectrometry and NMR, and cell-based imaging and biochemical approaches to validate signaling mechanisms and their impact on cell behavior. For details on our current projects, check out our “Research” page.

Lab News

  • August 2020 - Congratulations to Laurel, Jake, and Natalie for their review "Dynamic Equilibria in Protein Kinases."
  • August 2020 - Welcome to Biochemistry rotation student Sashi Weerawarana!
  • August 2020 - Congratulations to Andrew Kavran for successfully defending his PhD thesis!
  • May 2020 - Kristyn Hayashi joins the lab!
  • March 2020.- Welcome to Biochemistry rotation student Riley Ill!
  • October 2020 - Welcome to Biochemistry rotation student Kristyn Hayashi!
  • August 2020 - Welcome to Biochemistry rotation student Logan McCoy!
  • July 2020 - Congratulations to Dylan for acceptance of his paper to Biochemistry
  • May 2020 - Members of the Ahn lab return to on-campus research after closing the lab due to COVID19.
  • January 2020 - Welcome to our Biochemistry rotation student Victor Passanisi!
  • October 2019 - Welcome to undergraduate Jake Anderson, who will be working with Laurel on ERK inhibitors!
  • August 2019 - Welcome to our new technician Eleonora Claessens, Biochemistry rotation student Kevin Clopper, and new undergrad researcher Jason Haw!
  • July 2019 - Congratulations to Laurel, Maria, Dylan, Jen, and Johannes, et al., on acceptance and publication of their paper in PNAS
  • June 2019 - Congratulations to Pelle Simpson for completing his Masters of Science in Analytical Chemistry from the University of Amsterdam!