Our paper "Contributions of microtubule dynamic instability and rotational diffusion to kinetochore capture" was published in final form today by the Biophysical Journal and highlighted on the Biophysical Journal website.
Microtubules, motors, and cross-linkers are important for bipolarity, but the mechanisms necessary and sufficient for spindle assembly remain unknown. We describe a physical model that exhibits de novo bipolar spindle formation.
Recent work has found that microtubule rotational diffusion about minus-end attachment points contributes to kinetochore capture in fission yeast, but the relative contributions of dynamic instability and rotational diffusion are not well understood.
Robert Blackwell's paper "Microscopic origins of anisotropic active stress in motor-driven nematic liquid crystals" was published in the latest issue of Soft Matter , and was selected for an inside cover image .
We study a physical model of filaments, crosslinking motors, and static crosslinkers to dissect the microscopic mechanisms of active stress generation in a two-dimensional system of orientationally aligned rods.