We present Brownian dynamics simulation results of driven semiflexible filaments with intrinsic curvature and investigate how the interplay between filament rigidity and radius of curvature can tune the self-organization behavior in homochiral systems and heterochiral mixtures.
We use simulations of driven ﬁlaments with tunable soft repulsion and rigidity in order to better understand how the interplay between ﬁlament flexibility and steric effects can lead to different active steady states.
We develop a computational model of fission-yeast mitosis using a course-grained Brownian Dynamic framework in conjunction with a force-dependent kinetic Monte Carlo algorithm to replicate the biorientation and segregation of chromosomes.
Our paper " Theory of Cytoskeletal Reorganization during Cross-Linker-Mediated Mitotic Spindle Assembly " was published in the May 7, 2019 edition of Biophysical Journal. Our video was highlighted on the front page of the journal's website .