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Chromosome biorientation modeling paper posted to bioRxiv

June 5, 2019

Our paper "Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling" was posted on the bioRxiv server.

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Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling

June 4, 2019

We develop a computational model of fission-yeast mitosis using a course-grained Brownian Dynamic framework in conjunction with a force-dependent kinetic Monte Carlo algorithm to replicate the biorientation and segregation of chromosomes.

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Cross-linker-mediated spindle assembly theory paper published in Biophysical Journal

May 7, 2019

Our paper " Theory of Cytoskeletal Reorganization during Cross-Linker-Mediated Mitotic Spindle Assembly " was published in the May 7, 2019 edition of Biophysical Journal. Our video was highlighted on the front page of the journal's website .

Model overview

Theory of cytoskeletal reorganization during crosslinker-mediated mitotic spindle assembly

May 7, 2019

We develop a torque-balance model that describes spindle assembly due to dynamic microtubule bundles, spindle-pole bodies, the nuclear envelope, and crosslinkers to predict spindle-assembly dynamics.

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Spindle assembly theory paper accepted by Biophysical Journal

March 6, 2019

Our paper "Theory of cytoskeletal reorganization during crosslinker-mediated mitotic spindle assembly" was accepted for publication at Biophysical Journal.

Model overview

Spindle assembly theory paper posted on biorxiv

Sept. 22, 2018

Our paper "Theory of cytoskeletal reorganization during crosslinker-mediated mitotic spindle assembly" was posted on the biorxiv preprint server today.

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Hui-Shun Kuan's paper published in Science, covered by New York Times

Aug. 16, 2018

Hui-Shun Kuan's paper with Daniel Goldman's group at Georgia Tech on traffic jam avoidance in fire ant tunnel digging has been published in Science and covered in the New York Times , Washington Post , Houston Chronicle , SF Gate , Scientific American , Science News , Ars Technica , BBC , Cosmos , Discover , Popular Mechanics , and Quartz .

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Collective clog control: Optimizing traffic flow in confined biological and robophysical excavation

Aug. 16, 2018

Groups of interacting active particles, insects, or humans can form clusters that hinder the goals of the collective. We find that digging performance can be robustly optimized within the constraints of narrow tunnels by individual idleness and retreating.

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Meredith Betterton spoke at BIRS workshop

Aug. 16, 2018

Meredith Betterton spoke on modeling spindle assembly and chromosome alignment in mitosis at the Banff International Research Station in Banff, Alberta. This workshop was called “ Mathematics of the Cell: Mechanical and Chemical Signaling across Scales ”.

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Meredith Betterton awarded NIGMS R01 grant

July 27, 2018

Meredith Betterton received project R01GM124371 from the NIGMS for experiments on kinesin-5 motors in spindle assembly. Congratulations!

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