Lab News
- Amy’s first graduate student, Phil Dittmer, successfully defended his Ph.D. The topic of his dissertation was the sub-cellular localization and dynamics of zinc (II) in biological health and signaling.
- Yan will present her recent work regarding the development of improved fluorescent protein based Zinc (II) sensors that can now measure metal homeostasis from picomolar to micromolar quantities. In addition, Jose was awarded a FASEB MARC travel
- Dawn Schaefer (Colorado School of Mines) and Emily Gibson report a simple fabrication technique to create all silicon/glass microfluidic devices using femtosecond laser ablation and anodic bonding. In a first application, they constructed a cell
- In this publication, several new genetically encoded sensors for Zinc (II) are presented based upon fluorescence resonance energy transfer (FRET). Sources and sinks for Zinc (II) are explored within the cell, including the cytosol, plasma membrane,
- Schuyler performed an in situ selection of a randomized amino acid linker library (10.2 million peptides) flanking three tandem optimized TC repeats. Read the article here.
- The connection between presenillin-1, calcium regulation, and Alzheimer’s disease may provide the key to understanding the long-observed, but poorly understood, link between Alzheimer’s disease and Calcium (II) dysregulation. In this study, Janet
- Featured in the news and views section of Nature Structural and Molecular Biology and published in Nature Methods, Schuyler uses a GFP complementation assay to tag effectors of the type-III secretion system in gram-negative bacteria, thereby
- Schuyler successfully defended his Ph.D. and has accepted a position as a post-doctoral associate with Dr. Jennifer Lippincott-Schwartz at the NIH in Maryland.
- Presenting at Janelia Farm's 'Novel Approaches to Bioimaging II' Conference, Kevin was asked to give a short talk regarding his recent work involving microfluidic based optimization of red-fluorescent proteins.