betterton
- Design principles of selective transport through biopolymer barriers paper has been accepted to Physics Review E.
Our paper "Bound-state diffusion due to binding to flexible polymers in a selective biofilter" was posted to bioRxiv.
Our paper "Length regulation of microtubule antiparallel overlaps by molecular motors" was posted on the bioRxiv server.
We demonstrate that bound mobility via tethered diffusion can be engineered into a synthetic gel using protein fragments derived from the nuclear pore complex.
We develop a theory of steady-state overlap length which depends on the filament plus-end motor concentration, determined by a balance between motor arrival and
motor departure in the absence of motor-driven sliding.
Our paper "Design principles of selective transport through biopolymer barriers" was posted to BioRxiv.
We develop a model motivated by features of the nuclear pore complex (NPC) which provides a framework to control binding-induced selective transport in bipolymeric materials.
Our paper "Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling" was posted on the bioRxiv server.
We develop a computational model of fission-yeast mitosis using a course-grained Brownian Dynamic framework in conjunction with a force-dependent kinetic Monte Carlo algorithm to replicate the biorientation and segregation of chromosomes.
Our paper "Theory of Cytoskeletal Reorganization during Cross-Linker-Mediated Mitotic Spindle Assembly" was published in the May 7, 2019 edition of Biophysical Journal. Our video was highlighted on the front page of the journal's website.