Spindle images

Spindle assembly modeling paper published by Science Advances

Jan. 20, 2017

Robert Blackwell's paper "Physical determinants of bipolar mitotic spindle assembly and stability in fission yeast" was published by Science Advances .

Spindle images.

Physical determinants of bipolar mitotic spindle assembly and stability in fission yeast

Jan. 20, 2017

Microtubules, motors, and cross-linkers are important for bipolarity, but the mechanisms necessary and sufficient for spindle assembly remain unknown. We describe a physical model that exhibits de novo bipolar spindle formation.

Fixed cell thumbnail

Zach Gergely's paper published by Molecular Biology of the Cell

Nov. 7, 2016

Zachary Gergely's paper "Kinesin-8 effects on mitotic microtubule dynamics contribute to spindle function in fission yeast" was published in final form by Molecular Biology of the Cell.

Phase portrait.

Hui-Shun Kuan's paper published by Physical Review E

Aug. 29, 2016

Hui-Shun Kuan's paper "Phase-plane analysis of the totally asymmetric simple exclusion process with binding kinetics and switching between antiparallel lanes" was published by Physical Review E .

Phase plane

Hui-Shun Kuan's paper accepted by Physical Review E

July 20, 2016

Hui-Shun Kuan's paper "Phase-plane analysis of the totally asymmetric simple exclusion process with binding kinetics and switching between antiparallel lanes" was accepted for publication at Physical Review E .

Model cartoon

Contributions of microtubule dynamic instability and rotational diffusion to kinetochore capture

June 24, 2016

Recent work has found that microtubule rotational diffusion about minus-end attachment points contributes to kinetochore capture in fission yeast, but the relative contributions of dynamic instability and rotational diffusion are not well understood.

Cartoon of kinetichore diffusion and capture inside nuclear envelope

Kinetochore capture preprint posted on arXiv

June 24, 2016

Our paper "Contributions of microtubule dynamic instability and rotational diffusion to kinetochore capture" was posted on the arXiv preprint server today.

Cartoon showing motor dynamics on anti-parallel MT

Hui-Shun Kuan's paper published by the Biophysical Journal

May 10, 2016

Hui-Shun Kuan's paper "Motor protein accumulation on antiparallel microtubule overlaps" was accepted by the Biophysical Journal .

Cell image

Zach Gergely's paper published online by Molecular Biology of the Cell

May 9, 2016

Zachary Gergely's paper "Kinesin-8 effects on mitotic microtubule dynamics contribute to spindle function in fission yeast" was published online by Molecular Biology of the Cell. .

Cell images

Kinesin-8 effects on mitotic microtubule dynamics contribute to spindle function in fission yeast

April 28, 2016

To better understand the role of kinesin-8 proteins in mitosis, we have studied the effects of deletion of the fission-yeast kinesin-8 proteins Klp5 and Klp6 on chromosome movements and spindle length dynamics.

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