Our newest publications
- Opioid trail: Tracking contributions to opioid use disorder from host genetics to the gut microbiome
- Viral-mediated expression of Erk2 in the nucleus accumbens regulates responses to rewarding and aversive stimuli
- Toll-like receptor 4 antagonists reduce cocaine-primed reinstatement of drug seeking
- Adenosine receptor stimulation inhibits methamphetamine-associated cue seeking
- Methamphetamine Activates Toll-Like Receptor 4 to Induce Central Immune Signaling within the Ventral Tegmental Area and Contributes to Extracellular Dopamine Increase in the Nucleus Accumbens Shell
- Effects of chronic caffeine exposure during adolescence and subsequent acute caffeine challenge during adulthood on rat brain serotonergic systems
- Effects of adolescent caffeine consumption on cocaine self-administration and reinstatement of cocaine seeking
- Role of dopamine D<sub>2</sub>-like receptors and their modulation by adenosine receptor stimulation in the reinstatement of methamphetamine seeking
- Activation of the Immune System During a Developmental Window May Provide a Link Between Early Life Stress and Future Susceptibility to Cocaine Abuse
- Effects of adenosine A<sub>2A</sub> receptor antagonists on cocaine-induced locomotion and cocaine seeking
What's happening with dopamine and adenosine?
- Spiny projection neurons exhibit transcriptional signatures within subregions of the dorsal striatum
- Boolean analysis shows a high proportion of dopamine D<sub>2</sub> receptors interacting with adenosine A<sub>2A</sub> receptors in striatal medium spiny neurons of mouse and non-human primate models of Parkinson's disease
- Low Dopamine D2 Receptor Expression Drives Gene Networks Related to GABA, cAMP, Growth and Neuroinflammation in Striatal Indirect Pathway Neurons
- The adenosine A<sub>2A</sub> receptor in the basal ganglia: Expression, heteromerization, functional selectivity and signalling
- Neuroprotective effects of osmotin in Parkinson's disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways
- Dopaminergic neuroprotective effects of inosine in MPTP-induced parkinsonian mice via brain-derived neurotrophic factor upregulation
- Targeting corticostriatal transmission for the treatment of cannabinoid use disorder
- Striatal astrocytic A2A-D2 receptor-receptor interactions and their role in neuropsychiatric disorders
- Caffeine plus haloperidol reduces fatigue in an experimental model of Parkinson's disease - a prospective to A<sub>2A</sub>R-D<sub>2</sub>R heterodimer antagonism
- Enhancement of adenosine A<sub>2A</sub> signaling improves dopamine D<sub>2</sub> receptor antagonist-induced dyskinesia <em>via</em> β-arrestin signaling
What's happening with neuroinflammation in addiction?
- Extracellular vesicles-Mediators of opioid use disorder?
- Microglia: The new player orchestrating cocaine-induced expression of calcium-permeable AMPA receptors
- Triggering Receptor Expressed on Myeloid Cells 2 Deficiency Exacerbates Methamphetamine-Induced Activation of Microglia and Neuroinflammation
- NF-kB Regulation and the Chaperone System Mediate Restorative Effects of the Probiotic <em>Lactobacillus fermentum</em> LF31 in the Small Intestine and Cerebellum of Mice with Ethanol-Induced Damage
- Methamphetamine (MA) use and MA-induced psychosis are associated with increasing aberrations in the compensatory immunoregulatory system, interleukin-1α, and CCL5 levels
- Cell-type brain-region specific changes in prefrontal cortex of a mouse model of alcohol dependence
- Perinatal morphine but not buprenorphine affects gestational and offspring neurobehavioral outcomes in mice
- Melatonin enhances the restoration of neurological impairments and cognitive deficits during drug withdrawal in methamphetamine-induced toxicity and endoplasmic reticulum stress in rats
- Aitongping patch could alleviate cancer pain via suppressing microglia activation and modulating the miR-150-5p/CXCL12 signaling
- Microglia-mediated calcium-permeable AMPAR accumulation in the nucleus accumbens drives hyperlocomotion during cocaine withdrawal