Biochemistry Shared Instrument Core

Welcome to the Biochemistry Shared Instrument Core at the University of Colorado Boulder!

The instrument core gives researchers of the CU community and from outside the university access to a multitude of state of the art instruments and techniques including EPR, CD and fluorescence spectroscopy, DLS, Sec-MALS and ITC. In addition it houses a variety of additional equipment, such as imaging systems, centrifuges, scintillation counter, sonicator and more.

The director of the core, Dr. Annette Erbse, has extensive knowledge of the instrumentation available and wide-ranging experience in biophysical and biochemical characterization of structure and function of biological macromolecules. Dr. Erbse is available for training but also provides support from project planning to experiment optimization to data evaluation and interpretation.

For information about the instruments, availability, terms of use, to discuss projects or to request training please contact Dr. Annette Erbse (see contact information below). The cost for supplies and consumables are the responsibility of the users. 

We accept projects from outside the university on a fee-for-service base. For more information and pricing please contact Dr. Annette Erbse (contact information below).

Our current list of instruments includes:

Electron Paramagnetic Resonance (EPR) Spectrometer All instruments

Circluar Dichroism (CD)/Fluorescense Spectrometer


Dynamic Light Scattering (DLS)

Multi-Angle Light Scattering (MALS)

Isothermal Titration Calorimeter (ITC)

Rapid-Mixing, Quenched Flow Apparatus

Imaging Systems (LAS 4000/Typhoon/Alphalmager)


Plate Reader


Emulsiflex C3 Homogenizer

Scintillation Counter

Various Centrifuges