Sleep and Chronobiology Laboratory

Administrative Research Center (ARC), Room A29

3100 Marine Street
Boulder, CO 80309-0554
phone: 303-735-1923
fax: 303-735-2864

Research Interests

  • Health and safety consequences of sleep and circadian disruption.

  • Influence of sleep and circadian rhythms on human physiology (neuroendocrine, metabolic and immune function) and behavior (sleepiness, memory, learning, mood, cognitive and motor performance) with application to public health and safety.

  • Countermeasures to improve sleep, wakefulness, and health.

Personnel

  • Director: Kenneth P. Wright Jr., Ph.D.
  • Assistant Research Professor: Josiane L. Broussard, Ph.D.
  • Postdoctoral Fellow: Christopher M. Depner, Ph.D.
  • Graduate Students: Andres Barandiaran, Taylor Marshall, Hannah K. Ritchie, M.S., Ellen B. Stothard, M.S.
  • Undergraduate Students: Brandon Abell, Diego Archuleta, Chelsea Arent, Paul Bisesi, Austin Blanchard, Alivia Blumenstein, Henry Charoen, Dasha Cogswell, Julie Compton, Kira Enloe, Monaz Engineer, Blake Kutz, Shannon Lanza, Julia Lip, Jessa Marsh, Katelyn O’mara, Joey Schultz, Chaison Snyder, Lauren Walters, Ben Wharton, Jessica Wu.
  • Professional Research Assistants: Molly Guerin, B.A., Jake Guzzetti, B.A., Jeffrey Higdon, B.A., Oliver Knauer, B.A., Emily Marbas, B.A., Sarah Morton, M.S., Gayle Wright, MSW, LCSW.
Back Row (L to R): Taylor Marshall, Sean Fitzsimmons, Ben Wharton, Jessa Marsh, Paul Bisesi, Diego Archuleta, Dr. Christopher Depner, Joey Schultz, Brandon Abell, Austin Blanchard, Jacob Guzzetti, Oliver Knauer, Dr. Kenneth P. Wright Jr.
Middle Row (L to R): Gayle Wright, Dasha Cogswell, Alivia Blumenstein, Chaison Snyder, Henry Charoen, Jeff Higdon, Kira Enloe, Chelsea Arent, Julie Compton, Andres Barandiaran, Ellen Stothard, Dr. Josiane Broussard
Front Row (L to R): Monaz Engineer, Lauren Walters, Shannon Lanza, Jessica Wu, Molly Guerin, Emily Marbas, Hannah Ritchie

Current Research Projects

  • Impact of sleep and circadian disruption on the human microbiome and related changes in human physiology and cognition.
  • Biomarkers for insufficient sleep and circadian rhythm disruption (metabolomics and proteomics).
  • Tissue specific alterations in response to insufficient sleep and circadian misalignment.
  • Influence of sleep loss, sleep inertia and circadian disruption on cognitive function.
  • Countermeasures to improve sleep and wakefulness.
  • Physiological and behavioral mechanisms by which insufficient sleep and circadian misalignment contributes to metabolic dysregulation.
  • Countermeasures to improve cardiometabolic health during insufficient sleep.
  • Student-athlete sleep, health and performance.
  • Early morning shift work and metabolic dysregulation.

Persons interested in volunteering to participate in one of these studies should visit the sleep study participant page.

Colorado Sleep and Circadian Research Symposium

  • Fourth Annual Colorado Sleep and Circadian Research Symposium
    June 1, 2017 8AM-3PM - Keynote Speaker: Prof. Mark Opp.
    More details to come soon.
  • Past meetings - June 2016 | 2015 | 2014

Opportunities for Undergraduate Students

  • The requirements for undergraduate students who want a research experience in our Laboratory are:
    • A strong desire to obtain research experiences prior to graduate school, medical school, or advanced study in a health-related field
    • Minimum commitment: One year
    • Minimum hours/week when testing subjects: 8-10 hours (includes journal club)
    • Minimum experience: No prior experience required
    • Must be willing to work with a team
    • Must be able to work various hours during the day, at night, and on weekends.

  • UROP, independent study, honors thesis, and concurrent BA-MS opportunities are available.

  • For more information, contact gayle.wright@colorado.edu.

Opportunities for Graduate Students and Postdoctoral Fellows

Videos

Camping Syncs Internal Clock with Nature (Entrainment of the Human Circadian Clock to the Natural Light-Dark Cycle). Production and Editing: Brandon R. Griffin.

Recent Publications

Funding

  • 2016-2018, NIH R01 HL132150 NIH/NHLBI, "Biomarkers of Insufficient Sleep and Sleepiness" (PI: Wright, Reisdorph).
  • 2015-2020, N00014-15-1-2809, Office of Naval Research (ONR), "The microbiome and responsiveness to stress: Countermeasure strategies for improving resilience to sleep and circadian disruption" (PI and Team Lead: Wright).
  • 2016-2020, NIH R01 HL135598, NIH/NHLBI, "Sleep and Blood Pressure-Related Endothelial Abnormalities" (PI: Wright, Desouza, Stauffer).
  • 2016-2019, NIH R01 HL131458, NIH/NHLBI, "HIV-1, Insufficient Sleep and Vascular Endothelial Dysfunction" (PI: Desouza, Connick; Wright Co-Investigator).
  • 2012-2018, NIH U01 HL111478, NIH/NHLBI, "Multi-Center Trial of Limiting PGY2&3 Resident Work Hours on Patient Safety" (PI (Colorado): Wright).
  • 2016-2018, Pac-12 Grant , "Health and Performance: Pac-12 Center for Student-Athlete Health and Performance” (PI: McQueen; Wright Co-Investigator).
  • 2016-2019, Mentored Research Scientist Development Award NIH K01 DK110138, NIH/NIDDK, "Effects of physical activity on cardiometabolic impairments associated with insufficient sleep" (PI: Broussard).
  • 2016-2018, University of Colorado, Vice Chancellor of Research Innovative Seed Grant Program (PI: Broussard).
  • 2011-2017, Society in Science—The Branco Weiss Fellowship (PI: Broussard).
  • 2017-2019, Postdoctoral Individual National Research Service Award, F32 DK111161, NIH/NIDDK, "Mechanisms of Insufficient Sleep Contributing to Metabolic Disease Risk and Impact from ‘Weekend Recovery’ Sleep" (PI: Depner).