Neurophysiology of Movement Laboratory

Carlson 202G

Department of Integrative Physiology
University of Colorado
Boulder, CO 80309-0354
phone: 303-492-4965
fax: 303-492-6778

Research Interests

The neuromuscular mechanisms that mediate the acute adjustments and chronic adaptations experienced by humans in response to physical activity. Current projects address three main topics:
  1. Aging - adaptations in neuromuscular properties with advancing age: (a) association between indices of health status and neuromuscular performance in healthy older adults; (b) PET-based imaging of glucose uptake by muscle during fatiguing contractions; (c) modulation of spinal reflex pathways during the performance of steady contractions.

  2. Handedness - control strategies used by left-handed individuals as indicated by motor unit recordings.

  3. Multiple sclerosis - the associations between MRI-based estimates of brain structure and function with the fatigue reported by individuals with multiple sclerosis.


Opportunities for Undergraduates

  • The requirements for undergraduate students who want a research experience in our Laboratory are:
    • A major in integrative physiology

    • Either have completed or be concurrently enrolled in IPHY 4720 (Neurophysiology)

    • Obtain UROP funding or enroll in independent study (IPHY 4860) for 8-10 hours/week for at least one semester.

  • For more information, contact Diba Mani at (


Recent Publications