cancer cells

Novel selective HDAC6 inhibitors: A promising therapy approach for cancer and beyond

Aug. 4, 2021

Histone deacetylases (HDACs) are important epigenetic regulators, which impact chromatin condensation and gene expression. Tumor development has been linked to HDAC gene mutations and altered expression of HDACs. Therefore, inhibitors of histone deacetylase enzymes (HDACi) have been developed as potential cancer therapeutics. The researchers of the University of Colorado developed a series of hydroxamic acid derivatives as HDAC6 selective inhibitors. There is extensive national and international patent coverage for this technology.

STED technology

Stimulated emission depletion (STED) microscopy with polarization-maintaining fiber

July 28, 2021

Researchers at the University of Colorado have come up with a method for STED microscopy of a fluorescent species in an object to be imaged, the fluorescent excitation wavelength a fluorescence depletion wavelength and a fluorescence emission wavelength. This makes for a more accurate examination where subjects are free to move naturally possible.

collin bunch

Meet the Venture Partners Team: Collin Bunch

July 28, 2021

Say hello to Program Coordinator Collin Bunch, who has been a member of the Venture Partners team for the past 1.5 years. He has experience as an entrepreneur, consultant and marketer.

Chemical depolymerization methods for depolymerization of poly(ethylene terephthalate) (PET)

Methods for chemical degradation of polyester polymers

June 30, 2021

Even though poly(ethylene terephthalate) (PET) is generally the most recovered plastic, the amount of waste PET that is recycled is still low, especially given the scale of use. The most commonly reported reason for the lack of recycling is the inaccessibility to recycling resources, and there is therefore a need for a more accessible way of sustainably recycling PET. CU Boulder researchers have produced new methods for the chemical recycling of end-use PET in batch, microwave and electrochemical reactors.

Monolithic Mode-Locked Laser

Monolithic mode-locked laser

June 30, 2021

Mode-locked lasers are imperative for the generation and application of coherent optical frequency combs. Low noise is necessary for many applications. However, the current super low noise MLLs are massive lab-bench systems and unusable in industry applications. This technology is an extremely low-noise, low-power and high-repetition rate mode-locked laser.

therapeutic proteins

Containers and methods for reducing cavitation of protein solutions

June 29, 2021

Despite well-controlled production and purification processes, protein particulates in therapeutic protein formulations may still arise from protein adsorption to the surfaces of containers such as vials and pre-filled syringes, as well as the mechanical stresses resulting from these containers being agitated, dropped, or roughly handled. Researchers at the University of Colorado have shown that hydrogel coatings are able to protect the protein formulation against mechanical stresses responsible for subsequent protein aggregation and particle formation.

Marta Zgagacz

Meet the Venture Partners Team: Marta Zgagacz

June 23, 2021

Say hello to Director of Licensing Marta Zgagacz, who has been a member of the Venture Partners team for the past seven years. While studying physics in grad school, she started a company with university researchers, took it public, then later returned to the university to help researchers commercialize their inventions—just as she had done years before.

phased array device

A portable phased array radar device based on dual-frequency liquid crystal technology

May 26, 2021

This phased array radar device is easy to produce, cheaper, and more efficient. It has a modular nature that makes swapping liquid crystal cells and printed circut boards easy.

tantala microscope

Tantala ring resonator and method for fabricating nonlinear photonic devices

May 26, 2021

This technology is a patent-pending method and process to utilize tantala material for nonlinear photonics. Tantala offers superior material properties for integrated nonlinear photonics compared to other materials such as silicon nitride.

josh bennett

Meet the Venture Partners Team: Joshua Bennett

May 26, 2021

Say hello to Licensing Manager Joshua Bennett, who has been a member of the Venture Partners team for the past two years. He helps manage the intellectual property portfolio (patents and copyrights) for CU Boulder physical science inventions.