Office 1: DUAN F529, Duane Physics Tower
Office 2: D214, JSC Biotech Bldg
Lab: Located in JSCBB C wing, 2nd floor
I currently study intrinsically disordered proteins using solution NMR. Proteins containing disordered domains perform many important cellular functions. The aggregations of some members of this family of proteins is implicated in neuodegenerative diseases such as Alzheimer's and Parkinson's diseases. My lab currently has two main projects, one to dissect the role of tubulin's C-terminal tail in microtubule structure and functions. The second focuses on selective transport through the nuclear pore complex. We are use microscopy, nuclear magentic resonance and other biophysical techniques complemented with modeling to approach these systems. This work includes using in cell NMR, a technique to study the structure and dynamics of proteins within living cells.