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Chromosome biorientation modeling paper posted to bioRxiv

June 5, 2019

Our paper "Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling" was posted on the bioRxiv server.

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Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling

June 4, 2019

We develop a computational model of fission-yeast mitosis using a course-grained Brownian Dynamic framework in conjunction with a force-dependent kinetic Monte Carlo algorithm to replicate the biorientation and segregation of chromosomes.

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Cross-linker-mediated spindle assembly theory paper published in Biophysical Journal

May 7, 2019

Our paper " Theory of Cytoskeletal Reorganization during Cross-Linker-Mediated Mitotic Spindle Assembly " was published in the May 7, 2019 edition of Biophysical Journal. Our video was highlighted on the front page of the journal's website .

Model overview

Theory of cytoskeletal reorganization during crosslinker-mediated mitotic spindle assembly

May 7, 2019

We develop a torque-balance model that describes spindle assembly due to dynamic microtubule bundles, spindle-pole bodies, the nuclear envelope, and crosslinkers to predict spindle-assembly dynamics.

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Spindle assembly theory paper accepted by Biophysical Journal

March 6, 2019

Our paper "Theory of cytoskeletal reorganization during crosslinker-mediated mitotic spindle assembly" was accepted for publication at Biophysical Journal.

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Shane Fiorenza and Adam Lamson gave talks at APS March Meeting 2019

March 4, 2019

Shane Fiorenza and Adam Lamson gave talks at APS March Meeting 2019 in Boston, MA. Shane presented his work on sliding and stalling in microtubule bundles, while Adam presented his work on a theory of cytoskeletal rearrangement and force generation.

AL profile

Adam Lamson attended QCBnet Cell Modeling Hackathon

Jan. 19, 2019

Adam Lamson attended the Cell Modeling Hackathon at Half Moon Bay, CA. This event was hosted by The Quantitative Cell Biology Network and funded by the National Science Foundation.

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Adam Lamson and Chris Edelmaier presented at the Rocky Mountain Yeast Meeting

Jan. 11, 2019

Adam Lamson and Chris Edelmaier presented their work on modeling mitotic spindle self-assembly at the Rocky Mountain Yeast Meeting held at Colorado State University.

AL profile

Adam Lamson completed comps 3 exam

Nov. 26, 2018

Adam Lamson has successfully completed his comps 3 exam. Congratulations!

Model overview

Spindle assembly theory paper posted on biorxiv

Sept. 22, 2018

Our paper "Theory of cytoskeletal reorganization during crosslinker-mediated mitotic spindle assembly" was posted on the biorxiv preprint server today.

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