Office: JSCBB D314
Mailbox: 596 UCB
Provides vision and direction for the Materials Science & Engineering Program (began July 2021)
Functional Tissue Engineering, Photopolymerization, Biomaterials
The overall research objective of my group is to combine novel cell scaffold development with mechanical cues to direct and guide tissue growth in the appropriate composition to yield a functional and integrated tissue. Tissues in the body are continually subjected to mechanical stresses. It is well known that cells detect and respond to mechanical stresses by metabolic alterations that are mediated through specific mechanotransduction pathways. Photopolymerized hydrogels offer a unique medium with which to design a wide array of scaffolds from different chemistries that exhibit a range of macroscopic properties and degradation profiles. We are interested in exploiting the hydrogel environment to study mechanotransduction pathways as well as developing novel scaffolds combined with mechanical conditioning for tissue engineering. In particular, our group is focused primarily on cartilage tissue engineering, but will soon be expanding into cardiac muscle tissue engineering.